Myint, Aye-Mu

The new ‘5-HT’ hypothesis of depression: Cell-mediated immune activation induces indoleamine 2,3-dioxygenase, which leads to lower plasma tryptophan and an increased synthesis of detrimental tryptophan catabolites (TRYCATs), both of which contribute to the onset of depression

Maes, M., Leonard, B. E., Myint, A. M., Kubera, M., & Verkerk, R. (2011) · Progress in Neuro-Psychopharmacology and Biological Psychiatry

Tryptophan and brain disordersTreatment of Major Depression

Cited by 700

The role of pro-inflammatory cytokines in neuroinflammation, neurogenesis and the neuroendocrine system in major depression

Kim, Y.-K., Na, K.-S., Myint, A.-M., & Leonard, B. E. (2016) · Progress in Neuro-Psychopharmacology and Biological Psychiatry

Tryptophan and brain disordersStress Responses and Cortisol

Cited by 620

Severe depression is associated with increased microglial quinolinic acid in subregions of the anterior cingulate gyrus: Evidence for an immune-modulated glutamatergic neurotransmission?

Steiner, J., Walter, M., Gos, T., Guillemin, G. J., Bernstein, H.-G., Sarnyai, Z., Mawrin, C., Brisch, R., Bielau, H., zu Schwabedissen, L., et al. (2011) · Journal of Neuroinflammation

Tryptophan and brain disordersNeuroinflammation and Neurodegeneration Mechanisms

Cited by 568

Kynurenine pathway in major depression: Evidence of impaired neuroprotection

Myint, A.-M., Kim, Y. K., Verkerk, R., Scharpé, S., Steinbusch, H., & Leonard, B. (2007) · Journal of Affective Disorders

Tryptophan and brain disordersTreatment of Major Depression

Cited by 527

Interleukin-1β: A New Regulator of the Kynurenine Pathway Affecting Human Hippocampal Neurogenesis

Zunszain, P. A., Anacker, C., Cattaneo, A., Choudhury, S., Musaelyan, K., Myint, A. M., Thuret, S., Price, J., & Pariante, C. M. (2012) · Neuropsychopharmacology

Tryptophan and brain disordersNeurogenesis and neuroplasticity mechanisms

Cited by 388

Imbalance between pro-inflammatory and anti-inflammatory cytokines in bipolar disorder

Kim, Y.-K., Jung, H.-G., Myint, A.-M., Kim, H., & Park, S.-H. (2007) · Journal of Affective Disorders

Bipolar Disorder and TreatmentTryptophan and brain disorders

Cited by 375

Th1, Th2, and Th3 cytokine alterations in major depression

MYINT, A., LEONARD, B., STEINBUSCH, H., & KIM, Y. (2005) · Journal of Affective Disorders

Tryptophan and brain disordersStress Responses and Cortisol

Cited by 371

Network beyond IDO in psychiatric disorders: Revisiting neurodegeneration hypothesis

Myint, A.-M., & Kim, Y.-K. (2014) · Progress in Neuro-Psychopharmacology and Biological Psychiatry

Tryptophan and brain disordersTreatment of Major Depression

Cited by 230

Attention-deficit hyperactivity disorder (ADHD) and glial integrity: S100B, cytokines and kynurenine metabolism-effects of medication

Oades, R. D., Dauvermann, M. R., Schimmelmann, B. G., Schwarz, M. J., & Myint, A.-M. (2010) · Behavioral and Brain Functions

Attention Deficit Hyperactivity DisorderTryptophan and brain disorders

Cited by 151

Insufficient glucocorticoid signaling and elevated inflammation in coronary heart disease patients with comorbid depression

Nikkheslat, N., Zunszain, P. A., Horowitz, M. A., Barbosa, I. G., Parker, J. A., Myint, A.-M., Schwarz, M. J., Tylee, A. T., Carvalho, L. A., & Pariante, C. M. (2015) · Brain Behavior and Immunity

Stress Responses and CortisolCardiac Health and Mental Health

Cited by 147

Neuropsychiatric disorders related to interferon and interleukins treatment

Myint, A. M., Schwarz, M. J., Steinbusch, H. W. M., & Leonard, B. E. (2009) · Metabolic Brain Disease

Tryptophan and brain disordersTreatment of Major Depression

Cited by 116

T-helper types 1, 2, and 3 cytokine interactions in symptomatic manic patients.

Kim, Y.-K., Myint, A.-M., Lee, B.-H., Han, C.-S., Lee, S.-W., Leonard, B. E., & Steinbusch, H. W. M. (2004) · Psychiatry Research

Bipolar Disorder and TreatmentTryptophan and brain disorders

Cited by 100

Kynurenine pathway in schizophrenia: pathophysiological and therapeutic aspects

Muller, N., Myint, A.-M., & J. Schwarz, M. (2011) · Current Pharmaceutical Design

Tryptophan and brain disordersSchizophrenia research and treatment

Cited by 94

Anti-inflammatory treatment in schizophrenia

Müller, N., Myint, A.-M., Krause, D., Weidinger, E., & Schwarz, M. J. (2013) · Progress in Neuro-Psychopharmacology and Biological Psychiatry

Tryptophan and brain disordersSchizophrenia research and treatment

Cited by 89

Does escitalopram reduce neurotoxicity in major depression?

Halaris, A., Myint, A.-M., Savant, V., Meresh, E., Lim, E., Guillemin, G., Hoppensteadt, D., Fareed, J., & Sinacore, J. (2015) · Journal of Psychiatric Research

Tryptophan and brain disordersTreatment of Major Depression

Cited by 86

Tryptophan Metabolism and Immunogenetics in Major Depression: A Role for Interferon-γ Gene

Myint, A. M., Bondy, B., Baghai, T. C., Eser, D., Nothdurfter, C., Schüle, C., Zill, P., Müller, N., Rupprecht, R., & Schwarz, M. J. (2013) · Brain, Behavior, and Immunity

Tryptophan and brain disordersTreatment of Major Depression

Cited by 74

The kynurenine pathway in major depression: Haplotype analysis of three related functional candidate genes

Claes, S., Myint, A.-M., Domschke, K., Del-Favero, J., Entrich, K., Engelborghs, S., De Deyn, P., Mueller, N., Baune, B., & Rothermundt, M. (2011) · Psychiatry Research

Tryptophan and brain disordersTreatment of Major Depression

Cited by 65

Reduced microglial immunoreactivity for endogenous NMDA receptor agonist quinolinic acid in the hippocampus of schizophrenia patients

Gos, T., Myint, A.-M., Schiltz, K., Meyer-Lotz, G., Dobrowolny, H., Busse, S., Müller, U. J., Mawrin, C., Bernstein, H.-G., Bogerts, B., et al. (2014) · Brain, Behavior, and Immunity

Tryptophan and brain disordersNeuroinflammation and Neurodegeneration Mechanisms

Cited by 49