Blank, Thomas

Innate immune memory in the brain shapes neurological disease hallmarks

Wendeln, A.-C., Degenhardt, K., Kaurani, L., Gertig, M., Ulas, T., Jain, G., Wagner, J., Häsler, L. M., Wild, K., Skodras, A., et al. (2018) · Nature

Neuroinflammation and Neurodegeneration MechanismsImmune responses and vaccinations

Cited by 956

Genetic Cell Ablation Reveals Clusters of Local Self-Renewing Microglia in the Mammalian Central Nervous System

Bruttger, J., Karram, K., Wörtge, S., Regen, T., Marini, F., Hoppmann, N., Klein, M., Blank, T., Yona, S., Wolf, Y., et al. (2015) · Immunity

Neuroinflammation and Neurodegeneration MechanismsNeurogenesis and neuroplasticity mechanisms

Cited by 634

Microbiota-derived acetate enables the metabolic fitness of the brain innate immune system during health and disease

Erny, D., Dokalis, N., Mezö, C., Castoldi, A., Mossad, O., Staszewski, O., Frosch, M., Villa, M., Fuchs, V., Mayer, A., et al. (2021) · Cell Metabolism

Neuroinflammation and Neurodegeneration MechanismsGut microbiota and health

Cited by 478

Altered microglia morphology and higher resilience to stress-induced depression-like behavior in CX3CR1-deficient mice

Hellwig, S., Brioschi, S., Dieni, S., Frings, L., Masuch, A., Blank, T., & Biber, K. (2016) · Brain, Behavior, and Immunity

Neuroinflammation and Neurodegeneration MechanismsTryptophan and brain disorders

Cited by 252

Gut microbiota drives age-related oxidative stress and mitochondrial damage in microglia via the metabolite N6-carboxymethyllysine

Mossad, O., Batut, B., Yilmaz, B., Dokalis, N., Mezö, C., Nent, E., Nabavi, L. S., Mayer, M., Maron, F. J. M., Buescher, J. M., et al. (2022) · Nature Neuroscience

Neuroinflammation and Neurodegeneration MechanismsGut microbiota and health

Cited by 241

USP18 lack in microglia causes destructive interferonopathy of the mouse brain

Goldmann, T., Zeller, N., Raasch, J., Kierdorf, K., Frenzel, K., Ketscher, L., Basters, A., Staszewski, O., Brendecke, S. M., Spiess, A., et al. (2015) · The EMBO Journal

Neuroinflammation and Neurodegeneration Mechanismsinterferon and immune responses

Cited by 223

A somatic mutation in erythro-myeloid progenitors causes neurodegenerative disease

Mass, E., Jacome-Galarza, C. E., Blank, T., Lazarov, T., Durham, B. H., Ozkaya, N., Pastore, A., Schwabenland, M., Chung, Y. R., Rosenblum, M. K., et al. (2017) · Nature

Neuroinflammation and Neurodegeneration MechanismsNeurogenesis and neuroplasticity mechanisms

Cited by 210

Histone Deacetylases 1 and 2 Regulate Microglia Function during Development, Homeostasis, and Neurodegeneration in a Context-Dependent Manner

Datta, M., Staszewski, O., Raschi, E., Frosch, M., Hagemeyer, N., Tay, T. L., Blank, T., Kreutzfeldt, M., Merkler, D., Ziegler-Waldkirch, S., et al. (2018) · Immunity

Neuroinflammation and Neurodegeneration MechanismsHistone Deacetylase Inhibitors Research

Cited by 206

Dendritic Cells Ameliorate Autoimmunity in the CNS by Controlling the Homeostasis of PD-1 Receptor+ Regulatory T Cells

Yogev, N., Frommer, F., Lukas, D., Kautz-Neu, K., Karram, K., Ielo, D., von Stebut, E., Probst, H.-C., van den Broek, M., Riethmacher, D., et al. (2012) · Immunity

T-cell and B-cell ImmunologyImmunotherapy and Immune Responses

Cited by 197

Stress-induced alternative splicing of acetylcholinesterase results in enhanced fear memory and long-term potentiation

Nijholt, I., Farchi, N., Kye, M., Sklan, E. H., Shoham, S., Verbeure, B., Owen, D., Hochner, B., Spiess, J., Soreq, H., et al. (2004) · Molecular Psychiatry

Memory and Neural MechanismsNeuroscience and Neuropharmacology Research

Cited by 126

Different effects of constitutive and induced microbiota modulation on microglia in a mouse model of Alzheimer’s disease

Mezö, C., Dokalis, N., Mossad, O., Staszewski, O., Neuber, J., Yilmaz, B., Schnepf, D., de Agüero, M. G., Ganal-Vonarburg, S. C., Macpherson, A. J., et al. (2020) · Acta Neuropathologica Communications

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 120

IκB kinase 2 determines oligodendrocyte loss by non-cell-autonomous activation of NF-κB in the central nervous system

Raasch, J., Zeller, N., van Loo, G., Merkler, D., Mildner, A., Erny, D., Knobeloch, K.-P., Bethea, J. R., Waisman, A., Knust, M., et al. (2011) · Brain

Multiple Sclerosis Research StudiesNF-κB Signaling Pathways

Cited by 106

Increased IL-8 Concentrations in the Cerebrospinal Fluid of Patients with Unipolar Depression

Kuzior, H., Fiebich, B. L., Yousif, N. M., Saliba, S. W., Ziegler, C., Nickel, K., Maier, S. J., Süß, P., Runge, K., Matysik, M., et al. (2020) · Comprehensive Psychiatry

Tryptophan and brain disordersTreatment of Major Depression

Cited by 41

Commensal microbiota divergently affect myeloid subsets in the mammalian central nervous system during homeostasis and disease

Sankowski, R., Ahmari, J., Mezö, C., Hrabě de Angelis, A. L., Fuchs, V., Utermöhlen, O., Buch, T., Blank, T., Gomez de Agüero, M., Macpherson, A. J., et al. (2021) · The EMBO Journal

Neuroinflammation and Neurodegeneration MechanismsGut microbiota and health

Cited by 32

Small-Conductance Ca2+-Activated Potassium Type 2 Channels Regulate the Formation of Contextual Fear Memory

Murthy, S. R. K., Sherrin, T., Jansen, C., Nijholt, I., Robles, M., Dolga, A. M., Andreotti, N., Sabatier, J.-M., Knaus, H.-G., Penner, R., et al. (2015) · PLOS ONE

Memory and Neural MechanismsIon channel regulation and function

Cited by 16