Köhler, Jens

KRAS Dimerization Impacts MEK Inhibitor Sensitivity and Oncogenic Activity of Mutant KRAS

Ambrogio, C., Köhler, J., Zhou, Z.-W., Wang, H., Paranal, R., Li, J., Capelletti, M., Caffarra, C., Li, S., Lv, Q., et al. (2018) · Cell

Protein Kinase Regulation and GTPase SignalingMelanoma and MAPK Pathways

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MPS1 inhibition primes immunogenicity of KRAS-LKB1 mutant lung cancer

Kitajima, S., Tani, T., Springer, B. F., Campisi, M., Osaki, T., Haratani, K., Chen, M., Knelson, E. H., Mahadevan, N. R., Ritter, J., et al. (2022) · Cancer Cell

Cancer Immunotherapy and Biomarkersinterferon and immune responses

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Comparative Analysis and Isoform-Specific Therapeutic Vulnerabilities of KRAS Mutations in Non–Small Cell Lung Cancer

Ricciuti, B., Son, J., Okoro, J. J., Mira, A., Patrucco, E., Eum, Y., Wang, X., Paranal, R., Wang, H., Lin, M., et al. (2022) · Clinical Cancer Research

Lung Cancer Treatments and MutationsProtein Kinase Regulation and GTPase Signaling

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Oncogenic RAS simultaneously protects against anti-EGFR antibody-dependent cellular cytotoxicity and EGFR signaling blockade

Kasper, S., Breitenbuecher, F., Reis, H., Brandau, S., Worm, K., Köhler, J., Paul, A., Trarbach, T., Schmid, K. W., & Schuler, M. (2013) · Oncogene

HER2/EGFR in Cancer ResearchProtein Kinase Regulation and GTPase Signaling

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Nadph-oxidase but not inducible nitric oxide synthase contributes to resistance in a murine staphylococcus aureus newman pneumonia model

Köhler, J., Breitbach, K., Renner, C., Heitsch, A.-K., Bast, A., van Rooijen, N., Vogelgesang, S., & Steinmetz, I. (2011) · Microbes and Infection

Neutrophil, Myeloperoxidase and Oxidative MechanismsRedox biology and oxidative stress

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