Scheller, Marina

DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction

Bröske, A.-M., Vockentanz, L., Kharazi, S., Huska, M. R., Mancini, E., Scheller, M., Kuhl, C., Enns, A., Prinz, M., Jaenisch, R., et al. (2009) · Nature Genetics

Hematopoietic Stem Cell TransplantationEpigenetics and DNA Methylation

Cited by 478

Lymphoid cell growth and transformation are suppressed by a key regulatory element of the gene encoding PU.1

Rosenbauer, F., Owens, B. M., Yu, L., Tumang, J. R., Steidl, U., Kutok, J. L., Clayton, L. K., Wagner, K., Scheller, M., Iwasaki, H., et al. (2006) · Nature Genetics

Genomics and Chromatin DynamicsHematopoietic Stem Cell Transplantation

Cited by 237

PU.1 Level-Directed Chromatin Structure Remodeling at the Irf8 Gene Drives Dendritic Cell Commitment

Schönheit, J., Kuhl, C., Gebhardt, M. L., Klett, F. F., Riemke, P., Scheller, M., Huang, G., Naumann, R., Leutz, A., Stocking, C., et al. (2013) · Cell Reports

Genomics and Chromatin DynamicsImmunotherapy and Immune Responses

Cited by 127

Altered Development and Cytokine Responses of Myeloid Progenitors in the Absence of Transcription Factor, Interferon Consensus Sequence Binding Protein

Scheller, M., Foerster, J., Heyworth, C. M., Waring, J. F., Löhler, J., Gilmore, G. L., Shadduck, R. K., Dexter, T. M., & Horak, I. (1999) · Blood

Chronic Myeloid Leukemia TreatmentsAcute Myeloid Leukemia Research

Cited by 111

DNMT3A clonal hematopoiesis-driver mutations induce cardiac fibrosis by paracrine activation of fibroblasts

Shumliakivska, M., Luxán, G., Hemmerling, I., Scheller, M., Li, X., Müller-Tidow, C., Schuhmacher, B., Sun, Z., Dendorfer, A., Debes, A., et al. (2024) · Nature Communications

Cardiac Fibrosis and RemodelingAcute Myeloid Leukemia Research

Cited by 76

Hotspot DNMT3A mutations in clonal hematopoiesis and acute myeloid leukemia sensitize cells to azacytidine via viral mimicry response

Scheller, M., Ludwig, A. K., Göllner, S., Rohde, C., Krämer, S., Stäble, S., Janssen, M., Müller, J.-A., He, L., Bäumer, N., et al. (2021) · Nature Cancer

Acute Myeloid Leukemia ResearchEpigenetics and DNA Methylation

Cited by 73

Inflammatory signals from fatty bone marrow support DNMT3A driven clonal hematopoiesis

Zioni, N., Bercovich, A. A., Chapal-Ilani, N., Bacharach, T., Rappoport, N., Solomon, A., Avraham, R., Kopitman, E., Porat, Z., Sacma, M., et al. (2023) · Nature Communications

Acute Myeloid Leukemia ResearchHematopoietic Stem Cell Transplantation

Cited by 67

Clonal hematopoiesis-associated motoric deficits caused by monocyte-derived microglia accumulating in aging mice

Kim, J.-S., Trzebanski, S., Shin, S.-H., Schori, L., Frumer Friedman, G. R., Ilani, N. C., Kadam, A., Vicario, R., Aust, O., Bugaeva, P., et al. (2025) · Cell Reports

Neuroinflammation and Neurodegeneration MechanismsAcute Myeloid Leukemia Research

Cited by 33