D’Hooge, Rudi

TUDCA, a Bile Acid, Attenuates Amyloid Precursor Protein Processing and Amyloid-β Deposition in APP/PS1 Mice

Nunes, A. F., Amaral, J. D., Lo, A. C., Fonseca, M. B., Viana, R. J. S., Callaerts-Vegh, Z., D’Hooge, R., & Rodrigues, C. M. P. (2012) · Molecular Neurobiology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 192

Cognition and hippocampal synaptic plasticity in mice with a homozygous tau deletion

Ahmed, T., Van der Jeugd, A., Blum, D., Galas, M.-C., D’Hooge, R., Buee, L., & Balschun, D. (2014) · Neurobiology of Aging

Alzheimer's disease research and treatmentsNeuroscience and Neuropharmacology Research

Cited by 137

Cognitive defects are reversible in inducible mice expressing pro-aggregant full-length human Tau

Van der Jeugd, A., Hochgräfe, K., Ahmed, T., Decker, J. M., Sydow, A., Hofmann, A., Wu, D., Messing, L., Balschun, D., D’Hooge, R., et al. (2012) · Acta Neuropathologica

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 135

Comment on “ApoE-Directed Therapeutics Rapidly Clear β-Amyloid and Reverse Deficits in AD Mouse Models”

Tesseur, I., Lo, A. C., Roberfroid, A., Dietvorst, S., Van Broeck, B., Borgers, M., Gijsen, H., Moechars, D., Mercken, M., Kemp, J., et al. (2013) · Science

Alzheimer's disease research and treatmentsCholinesterase and Neurodegenerative Diseases

Cited by 128

Deregulation of neuronal miRNAs induced by amyloid-β or TAU pathology

Sierksma, A., Lu, A., Salta, E., Vanden Eynden, E., Callaerts-Vegh, Z., D’Hooge, R., Blum, D., Buée, L., Fiers, M., & De Strooper, B. (2018) · Molecular Neurodegeneration

Alzheimer's disease research and treatmentsMicroRNA in disease regulation

Cited by 120

Chronic administration of AFQ056/Mavoglurant restores social behaviour in Fmr1 knockout mice

Gantois, I., Pop, A. S., de Esch, C. E. F., Buijsen, R. A. M., Pooters, T., Gomez-Mancilla, B., Gasparini, F., Oostra, B. A., D’Hooge, R., & Willemsen, R. (2013) · Behavioural Brain Research

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 100

The autism- and schizophrenia-associated protein CYFIP1 regulates bilateral brain connectivity and behaviour

Domínguez-Iturza, N., Lo, A. C., Shah, D., Armendáriz, M., Vannelli, A., Mercaldo, V., Trusel, M., Li, K. W., Gastaldo, D., Santos, A. R., et al. (2019) · Nature Communications

Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research

Cited by 96

Microglia lacking a peroxisomal β-oxidation enzyme chronically alter their inflammatory profile without evoking neuronal and behavioral deficits

Beckers, L., Geric, I., Stroobants, S., Beel, S., Van Damme, P., D’Hooge, R., & Baes, M. (2019) · Journal of Neuroinflammation

Neuroinflammation and Neurodegeneration MechanismsNeurological Disease Mechanisms and Treatments

Cited by 30

Increased Insoluble Amyloid-β Induces Negligible Cognitive Deficits in Old AppNL/NL Knock-In Mice

Salas, I. H., Callaerts-Vegh, Z., D’Hooge, R., Saido, T. C., Dotti, C. G., & De Strooper, B. (2018) · Journal of Alzheimer's Disease

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 12

TMEM55B promotes anterograde transport and distal axonal distribution of LAMP1-positive organelles

Rudnik, S., Li, C. H., Gottschling, D.-C., Veh, A., Barbosa, D. J., Richter, J., Stroobants, S., Schuster, B., Beck, I. M., Sedlack, R., et al. (2026) · bioRxiv (Cold Spring Harbor Laboratory)

Cellular transport and secretionAutophagy in Disease and Therapy

Cited by 0