Sage, Julien

Cellular mechanisms of tumour suppression by the retinoblastoma gene

Burkhart, D. L., & Sage, J. (2008) · Nature Reviews Cancer

Cancer-related Molecular PathwaysChromatin Remodeling and Cancer

Cited by 974

Targeting DNA damage response promotes antitumor immunity through STING-mediated T-cell activation in small cell lung cancer

Sen, T., Rodriguez, B. L., Chen, L., Corte, C. M. D., Morikawa, N., Fujimoto, J., Cristea, S., Nguyen, T., Diao, L., Li, L., et al. (2019) · Cancer Discovery

Cancer Immunotherapy and BiomarkersLung Cancer Research Studies

Cited by 902

Targeted disruption of the three Rb-related genes leads to loss of G 1 control and immortalization

Sage, J., Mulligan, G. J., Attardi, L. D., Miller, A., Chen, S., Williams, B., Theodorou, E., & Jacks, T. (2000) · Genes & Development

Cancer-related Molecular PathwaysTelomeres, Telomerase, and Senescence

Cited by 582

Acute mutation of retinoblastoma gene function is sufficient for cell cycle re-entry

Sage, J., Miller, A. L., Pérez-Mancera, P. A., Wysocki, J. M., & Jacks, T. (2003) · Nature

Cancer-related Molecular PathwaysTelomeres, Telomerase, and Senescence

Cited by 538

PDGF signalling controls age-dependent proliferation in pancreatic β-cells

Chen, H., Gu, X., Liu, Y., Wang, J., Wirt, S. E., Bottino, R., Schorle, H., Sage, J., & Kim, S. K. (2011) · Nature

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 278

Human hepatic organoids for the analysis of human genetic diseases

Guan, Y., Xu, D., Garfin, P. M., Ehmer, U., Hurwitz, M., Enns, G., Michie, S., Wu, M., Zheng, M., Nishimura, T., et al. (2017) · JCI Insight

Pluripotent Stem Cells ResearchPediatric Hepatobiliary Diseases and Treatments

Cited by 243

Cell type-specific effects of Rb deletion in the murine retina

MacPherson, D., Sage, J., Kim, T., Ho, D., McLaughlin, M. E., & Jacks, T. (2004) · Genes & Development

Retinal Development and DisordersOcular Oncology and Treatments

Cited by 222

Hematopoietic Stem Cell Quiescence Is Maintained by Compound Contributions of the Retinoblastoma Gene Family

Viatour, P., Somervaille, T. C., Venkatasubrahmanyam, S., Kogan, S., McLaughlin, M. E., Weissman, I. L., Butte, A. J., Passegué, E., & Sage, J. (2008) · Cell Stem Cell

Hematopoietic Stem Cell TransplantationMesenchymal stem cell research

Cited by 178

Perp Is a Mediator of p53-Dependent Apoptosis in Diverse Cell Types

Ihrie, R. A., Reczek, E., Horner, J. S., Khachatrian, L., Sage, J., Jacks, T., & Attardi, L. D. (2003) · Current Biology

Cancer-related Molecular PathwaysCell death mechanisms and regulation

Cited by 118

MicroRNA programs in normal and aberrant stem and progenitor cells

Arnold, C. P., Tan, R., Zhou, B., Yue, S.-B., Schaffert, S., Biggs, J. R., Doyonnas, R., Lo, M.-C., Perry, J. M., Renault, V. M., et al. (2011) · Genome Research

MicroRNA in disease regulationHematopoietic Stem Cell Transplantation

Cited by 65

Making Young Tumors Old: A New Weapon Against Cancer?

Sage, J. (2005) · Science of Aging Knowledge Environment

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 9