Aigner, Ludwig

The ageing systemic milieu negatively regulates neurogenesis and cognitive function

Villeda, S. A., Luo, J., Mosher, K. I., Zou, B., Britschgi, M., Bieri, G., Stan, T. M., Fainberg, N., Ding, Z., Eggel, A., et al. (2011) · Nature

Neurogenesis and neuroplasticity mechanismsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 1,763

Lipid droplet accumulating microglia represent a dysfunctional and pro-inflammatory state in the aging brain

Marschallinger, J., Iram, T., Zardeneta, M., Lee, S. E., Lehallier, B., Haney, M. S., Pluvinage, J. V., Mathur, V., Hahn, O., Morgens, D. W., et al. (2019) · Nature Neuroscience

Neuroinflammation and Neurodegeneration MechanismsAutophagy in Disease and Therapy

Cited by 1,414

Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain

Marschallinger, J., Iram, T., Zardeneta, M., Lee, S. E., Lehallier, B., Haney, M. S., Pluvinage, J. V., Mathur, V., Hahn, O., Morgens, D. W., et al. (2020) · Nature Neuroscience

Neuroinflammation and Neurodegeneration MechanismsAutophagy in Disease and Therapy

Cited by 1,384

Clonally expanded CD8 T cells patrol the cerebrospinal fluid in Alzheimer’s disease

Gate, D., Saligrama, N., Leventhal, O., Yang, A. C., Unger, M. S., Middeldorp, J., Chen, K., Lehallier, B., Channappa, D., De Los Santos, M. B., et al. (2020) · Nature

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 992

Human Adult Neurogenesis: Evidence and Remaining Questions

Kempermann, G., Gage, F. H., Aigner, L., Song, H., Curtis, M. A., Thuret, S., Kuhn, H. G., Jessberger, S., Frankland, P. W., Cameron, H. A., et al. (2018) · Cell Stem Cell

Neurogenesis and neuroplasticity mechanismsMemory and Neural Mechanisms

Cited by 790

Neuroinflammation in Alzheimer disease

Heneka, M. T., van der Flier, W. M., Jessen, F., Hoozemanns, J., Thal, D. R., Boche, D., Brosseron, F., Teunissen, C., Zetterberg, H., Jacobs, A. H., et al. (2025) · Nature Reviews Immunology

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 638

CD8+ T-cells infiltrate Alzheimer’s disease brains and regulate neuronal- and synapse-related gene expression in APP-PS1 transgenic mice

Unger, M. S., Li, E., Scharnagl, L., Poupardin, R., Altendorfer, B., Mrowetz, H., Hutter-Paier, B., Weiger, T. M., Heneka, M. T., Attems, J., et al. (2020) · Brain, Behavior, and Immunity

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 248

Brain and Retinal Pericytes: Origin, Function and Role

Trost, A., Lange, S., Schroedl, F., Bruckner, D., Motloch, K. A., Bogner, B., Kaser-Eichberger, A., Strohmaier, C., Runge, C., Aigner, L., et al. (2016) · Frontiers in Cellular Neuroscience

Barrier Structure and Function StudiesRetinal Diseases and Treatments

Cited by 244

Ageing abolishes the effects of fluoxetine on neurogenesis

Couillard-Despres, S., Wuertinger, C., Kandasamy, M., Caioni, M., Stadler, K., Aigner, R., Bogdahn, U., & Aigner, L. (2009) · Molecular Psychiatry

Neurogenesis and neuroplasticity mechanismsTreatment of Major Depression

Cited by 143

The maternal brain: an organ with peripartal plasticity

Hillerer, K. M., Jacobs, V. R., Fischer, T., & Aigner, L. (2014) · Neural Plasticity

Neurogenesis and neuroplasticity mechanismsMaternal Mental Health During Pregnancy and Postpartum

Cited by 120

TGF-β Signaling: A Therapeutic Target to Reinstate Regenerative Plasticity in Vascular Dementia?

Kandasamy, M., Anusuyadevi, M., Aigner, K. M., Unger, M. S., Kniewallner, K. M., Sousa, D. M. B. D., Altendorfer, B., Mrowetz, H., Bogdahn, U., & Aigner, L. (2020) · Aging and disease

Neurological Disease Mechanisms and TreatmentsBarrier Structure and Function Studies

Cited by 77

Novel role for SLPI in MOG-induced EAE revealed by spinal cord expression analysis

Mueller, A. M., Pedré, X., Stempfl, T., Kleiter, I., Couillard-Despres, S., Aigner, L., Giegerich, G., & Steinbrecher, A. (2008) · Journal of Neuroinflammation

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 61

Exploration of the Gut–Brain Axis through Metabolomics Identifies Serum Propionic Acid Associated with Higher Cognitive Decline in Older Persons

Neuffer, J., González-Domínguez, R., Lefèvre-Arbogast, S., Low, D. Y., Driollet, B., Helmer, C., Du Preez, A., de Lucia, C., Ruigrok, S. R., Altendorfer, B., et al. (2022) · Nutrients

Gut microbiota and healthDementia and Cognitive Impairment Research

Cited by 40