Zeh, Herbert J.

Autophagy promotes ferroptosis by degradation of ferritin

Hou, W., Xie, Y., Song, X., Sun, X., Lotze, M. T., Zeh, H. J., Kang, R., & Tang, D. (2016) · Autophagy

Ferroptosis and cancer prognosisAutophagy in Disease and Therapy

Cited by 2,332

HMGB1 in health and disease

Kang, R., Chen, R., Zhang, Q., Hou, W., Wu, S., Cao, L., Huang, J., Yu, Y., Fan, X.-G., Yan, Z., et al. (2014) · Molecular Aspects of Medicine

Advanced Glycation End Products researchImmune Response and Inflammation

Cited by 956

Autophagy-dependent ferroptosis drives tumor-associated macrophage polarization via release and uptake of oncogenic KRAS protein

Dai, E., Han, L., Liu, J., Xie, Y., Kroemer, G., Klionsky, D. J., Zeh, H. J., Kang, R., Wang, J., & Tang, D. (2020) · Autophagy

Immune cells in cancerFerroptosis and cancer prognosis

Cited by 613

Safety and Survival With GVAX Pancreas Prime and Listeria Monocytogenes –Expressing Mesothelin (CRS-207) Boost Vaccines for Metastatic Pancreatic Cancer

Le, D. T., Wang-Gillam, A., Picozzi, V., Greten, T. F., Crocenzi, T., Springett, G., Morse, M., Zeh, H., Cohen, D., Fine, R. L., et al. (2015) · Journal of Clinical Oncology

Immunotherapy and Immune ResponsesPancreatic and Hepatic Oncology Research

Cited by 611

HSPA5 Regulates Ferroptotic Cell Death in Cancer Cells

Zhu, S., Zhang, Q., Sun, X., Zeh, H. J., Lotze, M. T., Kang, R., & Tang, D. (2017) · Cancer Research

Ferroptosis and cancer prognosisCell death mechanisms and regulation

Cited by 576

A Combination of Molecular Markers and Clinical Features Improve the Classification of Pancreatic Cysts

Springer, S., Wang, Y., Dal Molin, M., Masica, D. L., Jiao, Y., Kinde, I., Blackford, A., Raman, S. P., Wolfgang, C. L., Tomita, T., et al. (2015) · Gastroenterology

Pancreatic and Hepatic Oncology ResearchCancer Genomics and Diagnostics

Cited by 477

HMGB1 release and redox regulates autophagy and apoptosis in cancer cells

Tang, D., Kang, R., Cheh, C.-W., Livesey, K. M., Liang, X., Schapiro, N. E., Benschop, R., Sparvero, L. J., Amoscato, A. A., Tracey, K. J., et al. (2010) · Oncogene

Advanced Glycation End Products researchCell death mechanisms and regulation

Cited by 461

Preoperative next-generation sequencing of pancreatic cyst fluid is highly accurate in cyst classification and detection of advanced neoplasia

Singhi, A. D., McGrath, K., Brand, R. E., Khalid, A., Zeh, H. J., Chennat, J. S., Fasanella, K. E., Papachristou, G. I., Slivka, A., Bartlett, D. L., et al. (2018) · Gut

Pancreatic and Hepatic Oncology ResearchCancer Genomics and Diagnostics

Cited by 405

Masquerader: High Mobility Group Box-1 and Cancer

Ellerman, J. E., Brown, C. K., de Vera, M., Zeh, H. J., Billiar, T., Rubartelli, A., & Lotze, M. T. (2007) · Clinical Cancer Research

Advanced Glycation End Products researchS100 Proteins and Annexins

Cited by 355

Safety and biologic response of pre-operative autophagy inhibition in combination with gemcitabine in patients with pancreatic adenocarcinoma

Boone, B. A., Bahary, N., Zureikat, A. H., Moser, A. J., Normolle, D. P., Wu, W.-C., Singhi, A. D., Bao, P., Bartlett, D. L., Liotta, L. A., et al. (2015) · Annals of Surgical Oncology

Pancreatic and Hepatic Oncology ResearchAutophagy in Disease and Therapy

Cited by 234

A randomized Phase II preoperative study of autophagy inhibition with high-dose hydroxychloroquine and gemcitabine/nab-paclitaxel in pancreatic cancer patients

Zeh, H. J., Bahary, N., Boone, B. A., Singhi, A. D., Miller-Ocuin, J. L., Normolle, D. P., Zureikat, A. H., Hogg, M. E., Bartlett, D. L., Lee, K. K., et al. (2020) · Clinical Cancer Research

Pancreatic and Hepatic Oncology ResearchAutophagy in Disease and Therapy

Cited by 233

Preoperative GNAS and KRAS Testing in the Diagnosis of Pancreatic Mucinous Cysts

Singhi, A. D., Nikiforova, M. N., Fasanella, K. E., McGrath, K. M., Pai, R. K., Ohori, N. P., Bartholow, T. L., Brand, R. E., Chennat, J. S., Lu, X., et al. (2014) · Clinical Cancer Research

Pancreatic and Hepatic Oncology ResearchNeuroendocrine Tumor Research Advances

Cited by 207

The expression of the receptor for advanced glycation endproducts (RAGE) is permissive for early pancreatic neoplasia

Kang, R., Loux, T., Tang, D., Schapiro, N. E., Vernon, P., Livesey, K. M., Krasinskas, A., Lotze, M. T., & Zeh, H. J. (2012) · Proceedings of the National Academy of Sciences

Advanced Glycation End Products researchPancreatic and Hepatic Oncology Research

Cited by 163

DAMPs, ageing, and cancer: The ‘DAMP Hypothesis’

Huang, J., Xie, Y., Sun, X., Zeh, H. J., Kang, R., Lotze, M. T., & Tang, D. (2015) · Ageing Research Reviews

Advanced Glycation End Products researchImmune Response and Inflammation

Cited by 144

SMAD4 loss is associated with response to neoadjuvant chemotherapy plus hydroxychloroquine in patients with pancreatic adenocarcinoma

Fei, N., Wen, S., Ramanathan, R., Hogg, M. E., Zureikat, A. H., Lotze, M. T., Bahary, N., Singhi, A. D., Zeh, H. J., & Boone, B. A. (2021) · Clinical and Translational Science

Pancreatic and Hepatic Oncology ResearchAutophagy in Disease and Therapy

Cited by 31

SRC kinase drives multidrug resistance induced by KRAS-G12C inhibition

Song, X., Zhou, Z., Elmezayen, A., Wu, R., Yu, C., Gao, B., Minna, J. D., Westover, K. D., Zeh, H. J., Kroemer, G., et al. (2024) · Science Advances

Lung Cancer Treatments and MutationsProtein Kinase Regulation and GTPase Signaling

Cited by 26

SRC at the Crossroads of KRAS Inhibitor Resistance: Mechanisms and Therapeutic Opportunities

Tian, H., Zhao, D., Zhou, Z., Kim, A., Huang, H., Lee, Y. J., Qu, Z., Kang, R., Zeh, H. J., Westover, K. D., et al. (2026) · Cancer Letters

Protein Kinase Regulation and GTPase SignalingLung Cancer Treatments and Mutations

Cited by 7