HMGB1 in health and disease

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Neutrophil Extracellular Traps Kill Bacteria

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The Inflammasomes

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Cellular senescence: when bad things happen to good cells

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Steatohepatitis: A tale of two “hits”?

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Release of chromatin protein HMGB1 by necrotic cells triggers inflammation

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Cancer statistics, 2011

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Severe Sepsis and Septic Shock

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Autophagy regulates lipid metabolism

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UNIDENTIFIED CURVED BACILLI ON GASTRIC EPITHELIUM IN ACTIVE CHRONIC GASTRITIS

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Mechanisms of mitophagy

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Resveratrol Reduces the Proinflammatory Effects and Lipopolysaccharide- Induced Expression of HMGB1 and TLR4 in RAW264.7 Cells

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A gene from the human sex-determining region encodes a protein with homology to a conserved DNA-binding motif

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Immunogenic cell death and DAMPs in cancer therapy

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Toll-like receptor 4–dependent contribution of the immune system to anticancer chemotherapy and radiotherapy

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Pancreatic cancer

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Molecular mechanisms of necroptosis: an ordered cellular explosion

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Eaten alive: a history of macroautophagy

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Death and anti-death: tumour resistance to apoptosis

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Identification of RIP1 kinase as a specific cellular target of necrostatins

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The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity

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Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis

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RAGE and amyloid-β peptide neurotoxicity in Alzheimer's disease

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Mammalian autophagy: core molecular machinery and signaling regulation

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Crosstalk in NF-κB Signaling Pathways

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Endonuclease G is an apoptotic DNase when released from mitochondria

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Mast cells

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Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease

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Programmed cell death involved in the schizolysigenous formation of the secretory cavity in Citrus sinensis L. (Osbeck)

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Molecular mechanisms of resistance and toxicity associated with platinating agents

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Extracellular histones are major mediators of death in sepsis

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Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis

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Autophagic cell death: the story of a misnomer

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HMGB1 is a therapeutic target for sterile inflammation and infection

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HMGB1 and RAGE in Inflammation and Cancer

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Molecular Reconstruction of Sleeping Beauty, a Tc1-like Transposon from Fish, and Its Transposition in Human Cells

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High Mobility Group 1 Protein (Hmg-1) Stimulates Proinflammatory Cytokine Synthesis in Human Monocytes

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Netting Neutrophils Are Major Inducers of Type I IFN Production in Pediatric Systemic Lupus Erythematosus

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Toll-like receptor 9–dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE

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Understanding RAGE, the receptor for advanced glycation end products

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Immune regulatory function of B cells.

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Monocytic cells hyperacetylate chromatin protein HMGB1 to redirect it towards secretion

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The RIP1/RIP3 Necrosome Forms a Functional Amyloid Signaling Complex Required for Programmed Necrosis

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Blockade of RAGE-amphoterin signalling suppresses tumour growth and metastases

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Immunogenic death of colon cancer cells treated with oxaliplatin

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Immunogenic and tolerogenic cell death

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Cholinergic agonists inhibit HMGB1 release and improve survival in experimental sepsis

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Pancreatic cancer biology and genetics

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Sensing and repairing DNA double-strand breaks

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Reversing established sepsis with antagonists of endogenous high-mobility group box 1

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The nuclear factor HMGB1 mediates hepatic injury after murine liver ischemia-reperfusion

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TREM-1 amplifies inflammation and is a crucial mediator of septic shock

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Development of several organs that require inductive epithelial-mesenchymal interactions is impaired in LEF-1-deficient mice.Preprint

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Neutrophil extracellular traps: Is immunity the second function of chromatin?

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Autophagy‐based unconventional secretory pathway for extracellular delivery of IL‐1β

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Endogenous HMGB1 regulates autophagy

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Autophagy suppresses tumor progression by limiting chromosomal instabilityPreprint

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High mobility group box 1 protein interacts with multiple Toll-like receptors

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The nuclear protein HMGB1 is secreted by monocytes via a non‐classical, vesicle‐mediated secretory pathway

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Toll-like receptor 4 and high-mobility group box-1 are involved in ictogenesis and can be targeted to reduce seizures

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Necrotic death as a cell fatePreprint

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From head to toes: the multiple facets of Sox proteins

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Histones: annotating chromatin

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Regulation of DNA-Dependent Activities by the Functional Motifs of the High-Mobility-Group Chromosomal Proteins

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Tumor-infiltrating DCs suppress nucleic acid–mediated innate immune responses through interactions between the receptor TIM-3 and the alarmin HMGB1

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TLR4 activation mediates kidney ischemia/reperfusion injury

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HMGB1 SIGNALS THROUGH TOLL-LIKE RECEPTOR (TLR) 4 AND TLR2

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A critical cysteine is required for HMGB1 binding to Toll-like receptor 4 and activation of macrophage cytokine release

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CD24 and Siglec-10 Selectively Repress Tissue Damage–Induced Immune Responses

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Eating Oneself and Uninvited Guests

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