Tempel, Wolfram

Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis

Anastasiou, D., Yu, Y., Israelsen, W. J., Jiang, J.-K., Boxer, M. B., Hong, B. S., Tempel, W., Dimov, S., Shen, M., Jha, A., et al. (2012) · Nature Chemical Biology

Cancer, Hypoxia, and MetabolismMetabolism, Diabetes, and Cancer

Cited by 816

Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation

Bian, C., Xu, C., Ruan, J., Lee, K. K., Burke, T. L., Tempel, W., Barsyte, D., Li, J., Wu, M., Zhou, B. O., et al. (2011) · The EMBO Journal

Genomics and Chromatin DynamicsCancer-related gene regulation

Cited by 281

Tet3 CXXC Domain and Dioxygenase Activity Cooperatively Regulate Key Genes for Xenopus Eye and Neural Development

Xu, Y., Xu, C., Kato, A., Tempel, W., Abreu, J. G., Bian, C., Hu, Y., Hu, D., Zhao, B., Cerovina, T., et al. (2012) · Cell

Epigenetics and DNA MethylationDevelopmental Biology and Gene Regulation

Cited by 271

Molecular basis of GID4-mediated recognition of degrons for the Pro/N-end rule pathway

Dong, C., Zhang, H., Li, L., Tempel, W., Loppnau, P., & Min, J. (2018) · Nature Chemical Biology

Ubiquitin and proteasome pathwaysProtein Degradation and Inhibitors

Cited by 111