Jeganathan, Karthik B.

Naturally occurring p16Ink4a-positive cells shorten healthy lifespan

Baker, D. J., Childs, B. G., Durik, M., Wijers, M. E., Sieben, C. J., Zhong, J., A. Saltness, R., Jeganathan, K. B., Verzosa, G. C., Pezeshki, A., et al. (2016) · Nature

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 2,876

BubR1 insufficiency causes early onset of aging-associated phenotypes and infertility in mice

Baker, D. J., Jeganathan, K. B., Cameron, J. D., Thompson, M., Juneja, S., Kopecka, A., Kumar, R., Jenkins, R. B., de Groen, P. C., Roche, P., et al. (2004) · Nature Genetics

Microtubule and mitosis dynamicsGenetics, Aging, and Longevity in Model Organisms

Cited by 731

Opposing roles for p16Ink4a and p19Arf in senescence and ageing caused by BubR1 insufficiency

Baker, D. J., Perez-Terzic, C., Jin, F., Pitel, K. S., Niederländer, N. J., Jeganathan, K., Yamada, S., Reyes, S., Rowe, L., Hiddinga, H. J., et al. (2008) · Nature Cell Biology

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 408

p21 produces a bioactive secretome that places stressed cells under immunosurveillance

Sturmlechner, I., Zhang, C., Sine, C. C., van Deursen, E.-J., Jeganathan, K. B., Hamada, N., Grasic, J., Friedman, D., Stutchman, J. T., Can, I., et al. (2021) · Science

Cancer-related Molecular PathwaysImmune cells in cancer

Cited by 295

Early aging–associated phenotypes in Bub3/Rae1 haploinsufficient mice

Baker, D. J., Jeganathan, K. B., Malureanu, L., Perez-Terzic, C., Terzic, A., & van Deursen, J. M. A. (2006) · The Journal of Cell Biology

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 175

BubR1 N Terminus Acts as a Soluble Inhibitor of Cyclin B Degradation by APC/CCdc20 in Interphase

Malureanu, L. A., Jeganathan, K. B., Hamada, M., Wasilewski, L., Davenport, J., & van Deursen, J. M. (2009) · Developmental Cell

Microtubule and mitosis dynamicsCancer-related Molecular Pathways

Cited by 172