Ghirlando, Rodolfo

Structure of Human RNase H1 Complexed with an RNA/DNA Hybrid: Insight into HIV Reverse Transcription

Nowotny, M., Gaidamakov, S. A., Ghirlando, R., Cerritelli, S. M., Crouch, R. J., & Yang, W. (2007) · Molecular Cell

Enzyme Structure and FunctionHIV/AIDS drug development and treatment

Cited by 316

Role of Oligosaccharide Residues of IgG1-Fc in FcγRIIb Binding

Mimura, Y., Sondermann, P., Ghirlando, R., Lund, J., Young, S. P., Goodall, M., & Jefferis, R. (2001) · Journal of Biological Chemistry

Monoclonal and Polyclonal Antibodies ResearchGlycosylation and Glycoproteins Research

Cited by 236

Cryo-EM structures and atomic model of the HIV-1 strand transfer complex intasome

Passos, D. O., Li, M., Yang, R., Rebensburg, S. V., Ghirlando, R., Jeon, Y., Shkriabai, N., Kvaratskhelia, M., Craigie, R., & Lyumkis, D. (2017) · Science

HIV Research and TreatmentHIV/AIDS drug development and treatment

Cited by 202

Molecular Architecture and Functional Model of the Complete Yeast ESCRT-I Heterotetramer

Kostelansky, M. S., Schluter, C., Tam, Y. Y. C., Lee, S., Ghirlando, R., Beach, B., Conibear, E., & Hurley, J. H. (2007) · Cell

Cellular transport and secretionUbiquitin and proteasome pathways

Cited by 172

Structural and Functional Organization of the ESCRT-I Trafficking Complex

Kostelansky, M. S., Sun, J., Lee, S., Kim, J., Ghirlando, R., Hierro, A., Emr, S. D., & Hurley, J. H. (2006) · Cell

Cellular transport and secretionUbiquitin and proteasome pathways

Cited by 115

GATA Zinc Finger Interactions Modulate DNA Binding and Transactivation

Trainor, C. D., Ghirlando, R., & Simpson, M. A. (2000) · Journal of Biological Chemistry

Genomics and Chromatin DynamicsHemoglobinopathies and Related Disorders

Cited by 103

Allosteric control of hemoglobin S fiber formation by oxygen and its relation to the pathophysiology of sickle cell disease

Henry, E. R., Cellmer, T., Dunkelberger, E. B., Metaferia, B., Hofrichter, J., Li, Q., Ostrowski, D., Ghirlando, R., Louis, J. M., Moutereau, S., et al. (2020) · Proceedings of the National Academy of Sciences

Hemoglobinopathies and Related DisordersHemoglobin structure and function

Cited by 65

HIV-1 matrix-tRNA complex structure reveals basis for host control of Gag localization

Bou-Nader, C., Muecksch, F., Brown, J. B., Gordon, J. M., York, A., Peng, C., Ghirlando, R., Summers, M. F., Bieniasz, P. D., & Zhang, J. (2021) · Cell Host & Microbe

HIV Research and TreatmentHIV/AIDS drug development and treatment

Cited by 48

Functional and structural characterization of a dense core secretory granule sorting domain from the PC1/3 protease

Dikeakos, J. D., Di Lello, P., Lacombe, M.-J., Ghirlando, R., Legault, P., Reudelhuber, T. L., & Omichinski, J. G. (2009) · Proceedings of the National Academy of Sciences

Cellular transport and secretionProtein Structure and Dynamics

Cited by 40

HIV-1 Integrase Assembles Multiple Species of Stable Synaptic Complex Intasomes That Are Active for Concerted DNA Integration In vitro

Li, M., Yang, R., Chen, X., Wang, H., Ghirlando, R., Dimitriadis, E. K., & Craigie, R. (2024) · Journal of Molecular Biology

HIV Research and TreatmentHIV/AIDS drug development and treatment

Cited by 18

GATA-1 Bends DNA in a Site-independent Fashion

Ghirlando, R., & Trainor, C. D. (2000) · Journal of Biological Chemistry

Protein Structure and DynamicsDiffusion and Search Dynamics

Cited by 18

Transposase N-terminal phosphorylation and asymmetric transposon ends inhibit piggyBac transposition in mammalian cells

Luo, W., Hickman, A. B., Genzor, P., Ghirlando, R., Furman, C. M., Menshikh, A., Haase, A., Dyda, F., & Wilson, M. H. (2022) · Nucleic Acids Research

CRISPR and Genetic EngineeringAnimal Genetics and Reproduction

Cited by 13

Structural Insights into Cir-mediated Killing by the Antimicrobial Protein Microcin V

Maurakis, S. A., O’Donnell, A. C., Botos, I., Ghirlando, R., Davies, B. W., & Buchanan, S. K. (2025) · Communications Biology

Antimicrobial Peptides and ActivitiesBacterial Genetics and Biotechnology

Cited by 3

Structural insights into Cir-mediated killing by the antimicrobial protein Microcin V

Maurakis, S. A., O’Donnell, A. C., Botos, I., Ghirlando, R., Davies, B. W., & Buchanan, S. K. (2025) · Communications Biology

Antimicrobial Peptides and ActivitiesBacterial Genetics and Biotechnology

Cited by 3

APOE genotypes differentially remodel the astrocytic lipid droplet proteome to shape lipid droplet dynamics

Cuní-López, C., Root, J. T., Hao, Y., Blomberg, N., Koppes-den Hertog, S. J., Sacks, D., Trujillo, A. E., Ghirlando, R., Kowal, I., Epstein, J., et al. (2026) · Nature Communications

Lipid metabolism and biosynthesisAlzheimer's disease research and treatments

Cited by 0