Ho, Samuel B.

Allosteric inhibition of SHP2 phosphatase inhibits cancers driven by receptor tyrosine kinases

Chen, Y.-N. P., LaMarche, M. J., Chan, H. M., Fekkes, P., Garcia-Fortanet, J., Acker, M. G., Antonakos, B., Chen, C. H.-T., Chen, Z., Cooke, V. G., et al. (2016) · Nature

Protein Tyrosine PhosphatasesProtein Kinase Regulation and GTPase Signaling

Cited by 925

A gp130–Src–YAP module links inflammation to epithelial regeneration

Taniguchi, K., Wu, L.-W., Grivennikov, S. I., de Jong, P. R., Lian, I., Yu, F.-X., Wang, K., Ho, S. B., Boland, B. S., Chang, J. T., et al. (2015) · Nature

Cytokine Signaling Pathways and InteractionsHippo pathway signaling and YAP/TAZ

Cited by 633

Disordered methionine metabolism in MTAP/CDKN2A-deleted cancers leads to dependence on PRMT5

Mavrakis, K. J., McDonald, E. R., Schlabach, M. R., Billy, E., Hoffman, G. R., deWeck, A., Ruddy, D. A., Venkatesan, K., Yu, J., McAllister, G., et al. (2016) · Science

Cancer-related gene regulationRNA modifications and cancer

Cited by 607

Supplementation of Saturated Long-Chain Fatty Acids Maintains Intestinal Eubiosis and Reduces Ethanol-induced Liver Injury in Mice

Chen, P., Torralba, M., Tan, J., Embree, M., Zengler, K., Stärkel, P., van Pijkeren, J.-P., DePew, J., Loomba, R., Ho, S. B., et al. (2015) · Gastroenterology

Gut microbiota and healthAlcohol Consumption and Health Effects

Cited by 322

Dysbiosis‐induced intestinal inflammation activates tumor necrosis factor receptor I and mediates alcoholic liver disease in mice

Chen, P., Stärkel, P., Turner, J. R., Ho, S. B., & Schnabl, B. (2015) · Hepatology

Alcohol Consumption and Health EffectsGut microbiota and health

Cited by 312

Allosteric inhibition of SHP2: identification of a potent, selective, and orally efficacious phosphatase inhibitor

Garcia Fortanet, J., Chen, C. H.-T., Chen, Y.-N. P., Chen, Z., Deng, Z., Firestone, B., Fekkes, P., Fodor, M., Fortin, P. D., Fridrich, C., et al. (2016) · Journal of Medicinal Chemistry

Protein Tyrosine PhosphatasesProtein Kinase Regulation and GTPase Signaling

Cited by 298

Gastric acid suppression promotes alcoholic liver disease by inducing overgrowth of intestinal Enterococcus

Llorente, C., Jepsen, P., Inamine, T., Wang, L., Bluemel, S., Wang, H. J., Loomba, R., Bajaj, J. S., Schubert, M. L., Sikaroodi, M., et al. (2017) · Nature Communications

Gut microbiota and healthAlcohol Consumption and Health Effects

Cited by 257

Deficiency of intestinal mucin-2 ameliorates experimental alcoholic liver disease in mice

Hartmann, P., Chen, P., Wang, H. J., Wang, L., McCole, D. F., Brandl, K., Stärkel, P., Belzer, C., Hellerbrand, C., Tsukamoto, H., et al. (2013) · Hepatology

Alcohol Consumption and Health EffectsGut microbiota and health

Cited by 246

Identification of TNO155, an Allosteric SHP2 Inhibitor for the Treatment of Cancer

LaMarche, M. J., Acker, M., Argintaru, A., Bauer, D., Boisclair, J., Chan, H., Chen, C. H.-T., Chen, Y.-N., Chen, Z., Deng, Z., et al. (2020) · Journal of Medicinal Chemistry

Protein Tyrosine PhosphatasesProtein Kinase Regulation and GTPase Signaling

Cited by 231

Intestinal transgene delivery with native E. coli chassis allows persistent physiological changes

Russell, B. J., Brown, S. D., Siguenza, N., Mai, I., Saran, A. R., Lingaraju, A., Maissy, E. S., Dantas Machado, A. C., Pinto, A. F. M., Sanchez, C., et al. (2022) · Cell

Bacterial Cancer TherapyGut microbiota and health

Cited by 151

Selective induction of mucin‐3 by hypoxia in intestinal epithelia

Louis, N. A., Hamilton, K. E., Canny, G., Shekels, L. L., Ho, S. B., & Colgan, S. P. (2006) · Journal of Cellular Biochemistry

Digestive system and related healthGlycosylation and Glycoproteins Research

Cited by 144

Integrated care increases treatment and improves outcomes of patients with chronic hepatitis C virus infection and psychiatric illness or substance abuse

Ho, S. B., Bräu, N., Cheung, R., Liu, L., Sanchez, C., Sklar, M., Phelps, T. E., Marcus, S. G., Wasil, M. M., Tisi, A., et al. (2015) · Clinical Gastroenterology and Hepatology

Hepatitis C virus researchMental Health Treatment and Access

Cited by 118

Suicidal ideation during interferon-α2b and ribavirin treatment of patients with chronic hepatitis C

Dieperink, E., Ho, S. B., Tetrick, L., Thuras, P., Dua, K., & Willenbring, M. L. (2004) · General Hospital Psychiatry

Hepatitis C virus researchSuicide and Self-Harm Studies

Cited by 106

Effect of Obesogenic Medications on Weight‐Loss Outcomes in a Behavioral Weight‐Management Program

Desalermos, A., Russell, B., Leggett, C., Parnell, A., Ober, K., Hagerich, K., Gerlan, C., Ganji, G., Lee, E., Proudfoot, J. A., et al. (2019) · Obesity

Pharmacology and Obesity TreatmentObesity and Health Practices

Cited by 47

The hepatitis C self‐management programme: a randomized controlled trial

Groessl, E. J., Weingart, K. R., Stepnowsky, C. J., Gifford, A. L., Asch, S. M., & Ho, S. B. (2011) · Journal of Viral Hepatitis

Hepatitis C virus researchDiabetes Management and Education

Cited by 25

Development of the Hepatitis C Self-Management Program

Groessl, E. J., Weingart, K. R., Gifford, A. L., Asch, S. M., & Ho, S. B. (2011) · Patient Education and Counseling

Hepatitis C virus researchMedication Adherence and Compliance

Cited by 14