The hepatitis C self‐management programme: a randomized controlled trial
Abstract
Summary. Chronic hepatitis C (HCV) infection afflicts millions of people worldwide. While antiviral treatments are effective for some patients, many either cannot or choose not to receive antiviral treatment. Education about behavioural changes like alcohol avoidance and symptom management, in contrast, is universally recommended, particularly in HCV‐infected persons from disadvantaged groups where liver risk factors are most prevalent. Self‐management interventions are one option for fostering improved HCV knowledge and health‐related quality of life (HRQOL). One hundred and thirty‐two patients with VA with HCV (mean age of 54.6, 95% men, 41% ethnic minority, 83% unmarried, 72% unemployed/disabled, 48% homeless in last 5 years) were randomized to either a 6‐week self‐management workshop or an information‐only intervention. The weekly 2‐h self‐management sessions were based on cognitive‐behavioural principles and were adapted from an existing self‐management programme that has been efficacious with other chronic diseases. HCV‐specific modules were added. Outcomes including HRQOL, HCV knowledge, self‐efficacy, depression, energy and health distress were measured at baseline and 6 weeks later. Data were analysed using ANOVA. When compared to the information‐only group, participants attending the self‐management workshop improved more on HCV knowledge (P < 0.001), HCV self‐efficacy (P = 0.011), and SF‐36 energy/vitality (P = 0.040). Similar trends were found for SF‐36 physical functioning (P = 0.055) and health distress (P = 0.055). Attending the self‐management programme improved disease knowledge and HRQOL 6 weeks later in this disadvantaged population. The intervention can improve the health of people with hepatitis C, independent of antiviral therapy. Future research will study longer‐term outcomes, effects on antiviral treatment and costs.
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Research on self-efficacy beliefs in hepatitis C is scarce, and no studies were found that looked at these beliefs while patients were on antiviral treatment.
“Despite the importance of self-efficacy to medication adherence in other medical regimens, there is limited research in the HCV literature that examine self-efficacy beliefs, and no studies were identified that examined these beliefs during antiviral treatment (35;36).”
From Reliability and validity of a self‐efficacy instrument for hepatitis C antiviral treatment regimens (2012) · cites this paper as [36]
Self-efficacy beliefs are important targets for clinical intervention because they can be enhanced, leading to better self-management of chronic illness, including hepatitis C.
“Self-efficacy beliefs are important targets for clinical intervention, given that they can be enhanced, resulting in improved patient self-management of chronic illness, including chronic hepatitis C (35;36).”
From Reliability and validity of a self‐efficacy instrument for hepatitis C antiviral treatment regimens (2012) · cites this paper as [36]
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- Authors
- Groessl, E. J., Weingart, K. R., Stepnowsky, C. J., Gifford, A. L., Asch, S. M., & Ho, S. B.
- Affiliations
- University of California San Diego (US)
- VA San Diego Healthcare System (US)
- Boston University (US)
- University of California, Los Angeles (US)
- Corresponding author
- Groessl, E. J.
- Venue
- Journal of Viral Hepatitis
- Publisher
- Wiley
- Published
- 2011-04-06
- Volume
- 18
- Issue
- 5
- Pages
- 358-368
- ISSN
- 1352-0504 (ISSN-L)
- 1365-2893
- OpenAlex
- W2132404101
- Cited by
- 25
- References
- 63
- Citations by year
- 2026: 1 · 2024: 3 · 2019: 4 · 2017: 1 · 2016: 2 · 2015: 5 · 2014: 1 · 2013: 5 · 2012: 2
- FWCI
- 1.68
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Viral Hepatitis (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Health Services Research and Development
- Veterans Affairs San Diego Healthcare System
- Topics
- Health Sciences › Medicine › Hepatology › Hepatitis C virus research
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Education
- Health Sciences › Health Professions › Pharmacy › Nursing care and research
- Keywords
- chronic hepatitis C, self-management interventions, health-related quality of life, HCV knowledge, self-efficacy, cognitive-behavioural intervention, homeless veterans, disadvantaged groups, health education, depression, energy and vitality, health distress
- MeSH terms
- Analysis of Variance, Female, Follow-Up Studies, Humans, Health Knowledge, Attitudes, Practice, Male, Middle Aged, Patient Education as Topic, Prospective Studies, Quality of Life, Self Care, United States, Veterans, Cohort Studies, Treatment Outcome, Hepatitis C, Chronic
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