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Adagrasib in Non–Small-Cell Lung Cancer Harboring a KRAS G12C Mutation

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Preexistence and clonal selection of MET amplification in EGFR mutant NSCLC

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Identification of MRTX1133, a Noncovalent, Potent, and Selective KRAS G12D Inhibitor

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Identification of the Clinical Development Candidate MRTX849 , a Covalent KRASG12C Inhibitor for the Treatment of Cancer

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Anti-tumor efficacy of a potent and selective non-covalent KRASG12D inhibitor

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Adagrasib with or without Cetuximab in Colorectal Cancer with Mutated KRAS G12C

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Institutional implementation of clinical tumor profiling on an unselected cancer population

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Efficacy of a small-molecule inhibitor of KrasG12D in immunocompetent models of pancreatic cancer

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Mechanisms of Resistance to Oncogenic KRAS Inhibition in Pancreatic Cancer

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Molecular Characterization of Acquired Resistance to KRASG12C–EGFR Inhibition in Colorectal Cancer

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Adeno-to-squamous transition drives resistance to KRAS inhibition in LKB1 mutant lung cancer

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Discovery of tetrahydropyridopyrimidines as irreversible covalent inhibitors of KRAS-G12C with in vivo activity

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Genome-Wide CRISPR Screens Identify Multiple Synthetic Lethal Targets That Enhance KRASG12C Inhibitor Efficacy

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Combined Inhibition of SHP2 and CXCR1/2 Promotes Antitumor T-cell Response in NSCLC

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