Chapman, Edwin R.

SNAP-25, a t-SNARE which binds to both syntaxin and synaptobrevin via domains that may form coiled coils.

Chapman, E. R., An, S., Barton, N., & Jahn, R. (1994) · Journal of Biological Chemistry

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 295

Synaptotagmin-Mediated Bending of the Target Membrane Is a Critical Step in Ca2+-Regulated Fusion

Hui, E., Johnson, C. P., Yao, J., Dunning, F. M., & Chapman, E. R. (2009) · Cell

Cellular transport and secretionLipid Membrane Structure and Behavior

Cited by 291

Doc2 Is a Ca2+ Sensor Required for Asynchronous Neurotransmitter Release

Yao, J., Gaffaney, J. D., Kwon, S. E., & Chapman, E. R. (2011) · Cell

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 218

Ca2+ and synaptotagmin VII–dependent delivery of lysosomal membrane to nascent phagosomes

Czibener, C., Sherer, N. M., Becker, S. M., Pypaert, M., Hui, E., Chapman, E. R., Mothes, W., & Andrews, N. W. (2006) · The Journal of Cell Biology

Cellular transport and secretionCalcium signaling and nucleotide metabolism

Cited by 165

SNARE-complex disassembly by NSF follows synaptic-vesicle fusion

Littleton, J. T., Barnard, R. J. O., Titus, S. A., Slind, J., Chapman, E. R., & Ganetzky, B. (2001) · Proceedings of the National Academy of Sciences

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 140

Inhibition of TFG function causes hereditary axon degeneration by impairing endoplasmic reticulum structure

Beetz, C., Johnson, A., Schuh, A. L., Thakur, S., Varga, R.-E., Fothergill, T., Hertel, N., Bomba-Warczak, E., Thiele, H., Nürnberg, G., et al. (2013) · Proceedings of the National Academy of Sciences

Hereditary Neurological DisordersCellular transport and secretion

Cited by 106

Reconstituted synaptotagmin I mediates vesicle docking, priming, and fusion

Wang, Z., Liu, H., Gu, Y., & Chapman, E. R. (2011) · Journal of Cell Biology

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 98

Synaptotagmin C2B Domain Regulates Ca2+-triggered Fusion in Vitro

Gaffaney, J. D., Dunning, F. M., Wang, Z., Hui, E., & Chapman, E. R. (2008) · Journal of Biological Chemistry

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 75

Transport of a kinesin-cargo pair along microtubules into dendritic spines undergoing synaptic plasticity

McVicker, D. P., Awe, A. M., Richters, K. E., Wilson, R. L., Cowdrey, D. A., Hu, X., Chapman, E. R., & Dent, E. W. (2016) · Nature Communications

Neuroscience and Neuropharmacology ResearchMicrotubule and mitosis dynamics

Cited by 74

Synaptotagmin-7 Functions to Replenish Insulin Granules for Exocytosis in Human Islet β-Cells

Dolai, S., Xie, L., Zhu, D., Liang, T., Qin, T., Xie, H., Kang, Y., Chapman, E. R., & Gaisano, H. Y. (2016) · Diabetes

Pancreatic function and diabetesCellular transport and secretion

Cited by 55

Membrane compression by synaptic vesicle exocytosis triggers ultrafast endocytosis

Ogunmowo, T. H., Jing, H., Raychaudhuri, S., Kusick, G. F., Imoto, Y., Li, S., Itoh, K., Ma, Y., Jafri, H., Dalva, M. B., et al. (2023) · Nature Communications

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 51

Synaptotagmin 7 is targeted to the axonal plasma membrane through γ-secretase processing to promote synaptic vesicle docking in mouse hippocampal neurons

Vevea, J. D., Kusick, G. F., Courtney, K. C., Chen, E., Watanabe, S., & Chapman, E. R. (2021) · eLife

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 51

Phosphatidylinositol 4,5-bisphosphate drives Ca2+-independent membrane penetration by the tandem C2 domain proteins synaptotagmin-1 and Doc2β

Bradberry, M. M., Bao, H., Lou, X., & Chapman, E. R. (2019) · Journal of Biological Chemistry

Cellular transport and secretionLipid Membrane Structure and Behavior

Cited by 38

Rat and Drosophila Synaptotagmin 4 Have Opposite Effects during SNARE-catalyzed Membrane Fusion

Wang, Z., & Chapman, E. R. (2010) · Journal of Biological Chemistry

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 32

The juxtamembrane linker of synaptotagmin 1 regulates Ca2+ binding via liquid-liquid phase separation

Mehta, N., Mondal, S., Watson, E. T., Cui, Q., & Chapman, E. R. (2024) · Nature Communications

Cellular transport and secretionLipid Membrane Structure and Behavior

Cited by 28

All‐optical monitoring of excitation–secretion coupling demonstrates that SV2A functions downstream of evoked Ca2+ entry

Bradberry, M. M., & Chapman, E. R. (2022) · The Journal of Physiology

Neuroscience and Neuropharmacology ResearchCellular transport and secretion

Cited by 16

Synaptotagmin 7 docks synaptic vesicles to support facilitation and Doc2α-triggered asynchronous release

Wu, Z., Kusick, G. F., Berns, M. M. M., Raychaudhuri, S., Itoh, K., Walter, A. M., Chapman, E. R., & Watanabe, S. (2022) · bioRxiv (Cold Spring Harbor Laboratory)

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 13