Pouwels, Jeroen

SHARPIN is an endogenous inhibitor of β1-integrin activation

Rantala, J. K., Pouwels, J., Pellinen, T., Veltel, S., Laasola, P., Mattila, E., Potter, C. S., Duffy, T., Sundberg, J. P., Kallioniemi, O., et al. (2011) · Nature Cell Biology

Cell Adhesion Molecules ResearchCellular Mechanics and Interactions

Cited by 201

SHARPIN regulates uropod detachment in migrating lymphocytes

Pouwels, J., De Franceschi, N., Rantakari, P., Auvinen, K., Karikoski, M., Mattila, E., Potter, C., Sundberg, J. P., Hogg, N., Gahmberg, C. G., et al. (2013) · Cell Reports

Cell Adhesion Molecules ResearchChemokine receptors and signaling

Cited by 55

Mutually exclusive roles of SHARPIN in integrin inactivation and NF-κB signaling

De Franceschi, N., Peuhu, E., Parsons, M., Rissanen, S., Vattulainen, I., Salmi, M., Ivaska, J., & Pouwels, J. (2015) · PLOS ONE

Cell Adhesion Molecules ResearchNF-κB Signaling Pathways

Cited by 22

The Sharpin interactome reveals a role for Sharpin in lamellipodium formation via the Arp2/3 complex

Khan, M. H., Salomaa, S. I., Jacquemet, G., Butt, U., Miihkinen, M., Deguchi, T., Kremneva, E., Lappalainen, P., Humphries, M. J., & Pouwels, J. (2017) · Journal of Cell Science

Cellular Mechanics and InteractionsCell Adhesion Molecules Research

Cited by 14

SHARPIN S146 phosphorylation mediates ARP2/3 interaction, cancer cell invasion and metastasis

Butt, U., Khan, M. H., Pouwels, J., & Westermarck, J. (2022) · Journal of Cell Science

Protein Kinase Regulation and GTPase SignalingCellular Mechanics and Interactions

Cited by 6

SHARPIN serine 146 phosphorylation mediates ARP2/3 interaction, cancer cell invasion and metastasis

Butt, U., Khan, M. H., Pouwels, J., & Westermarck, J. (2022) · bioRxiv (Cold Spring Harbor Laboratory)

Protein Kinase Regulation and GTPase SignalingCellular Mechanics and Interactions

Cited by 6

Ovarian Cancers with Low CIP2A Tumor Expression Constitute an APR-246–Sensitive Disease Subtype

Cvrljevic, A. N., Butt, U., Huhtinen, K., Grönroos, T. J., Böckelman, C., Lassus, H., Butzow, R., Haglund, C., Kaipio, K., Arsiola, T., et al. (2022) · Molecular Cancer Therapeutics

Ovarian cancer diagnosis and treatmentCancer Mechanisms and Therapy

Cited by 5

Ovarian cancers with low CIP2A tumor expression constitute an APR-246 sensitive disease subtype

Cvrljevic, A. N., Butt, U., Huhtinen, K., Grönroos, T. J., Böckelman, C., Lassus, H., Kaipio, K., Arsiola, T., Laajala, T. D., Connolly, D. C., et al. (2021) · bioRxiv (Cold Spring Harbor Laboratory)

Ovarian cancer diagnosis and treatmentCancer Mechanisms and Therapy

Cited by 5