Rossman, Kent L.

GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors

Rossman, K. L., Der, C. J., & Sondek, J. (2005) · Nature Reviews Molecular Cell Biology

Protein Kinase Regulation and GTPase SignalingCellular transport and secretion

Cited by 1,697

Increasing complexity of Ras signaling

Campbell, S. L., Khosravi-Far, R., Rossman, K. L., Clark, G. J., & Der, C. J. (1998) · Oncogene

Protein Kinase Regulation and GTPase SignalingProtein Tyrosine Phosphatases

Cited by 1,079

RAS isoforms and mutations in cancer at a glance

Hobbs, G. A., Der, C. J., & Rossman, K. L. (2016) · Journal of Cell Science

Protein Kinase Regulation and GTPase SignalingProtein Tyrosine Phosphatases

Cited by 973

Rho guanine nucleotide exchange factors: regulators of Rho GTPase activity in development and disease

Cook, D. R., Rossman, K. L., & Der, C. J. (2014) · Oncogene

Protein Kinase Regulation and GTPase SignalingCellular transport and secretion

Cited by 378

Crystal structure of Rac1 in complex with the guanine nucleotide exchange region of Tiam1

Worthylake, D. K., Rossman, K. L., & Sondek, J. (2000) · Nature

Protein Kinase Regulation and GTPase SignalingReceptor Mechanisms and Signaling

Cited by 355

Rho family proteins and Ras transformation: the RHOad less traveled gets congested

Zohn, I. M., Campbell, S. L., Khosravi-Far, R., Rossman, K. L., & Der, C. J. (1998) · Oncogene

Protein Kinase Regulation and GTPase SignalingCellular transport and secretion

Cited by 352

A crystallographic view of interactions between Dbs and Cdc42: PH domain‐assisted guanine nucleotide exchange

Rossman, K. L., Worthylake, D. K., Snyder, J. T., Siderovski, D. P., Campbell, S. L., & Sondek, J. (2002) · The EMBO Journal

Protein Kinase Regulation and GTPase SignalingCellular transport and secretion

Cited by 222

Structural basis for the selective activation of Rho GTPases by Dbl exchange factors

Snyder, J. T., Worthylake, D. K., Rossman, K. L., Betts, L., Pruitt, W. M., Siderovski, D. P., Der, C. J., & Sondek, J. (2002) · Nature Structural Biology

Protein Kinase Regulation and GTPase SignalingCellular transport and secretion

Cited by 209

A Steric-Inhibition Model for Regulation of Nucleotide Exchange via the Dock180 Family of GEFs

Lu, M., Kinchen, J. M., Rossman, K. L., Grimsley, C., Hall, M., Sondek, J., Hengartner, M. O., Yajnik, V., & Ravichandran, K. S. (2005) · Current Biology

Protein Kinase Regulation and GTPase SignalingCellular transport and secretion

Cited by 102

Molecular basis for Rac1 recognition by guanine nucleotide exchange factors.

Karnoub, A. E., Worthylake, D. K., Rossman, K. L., Pruitt, W. M., Campbell, S. L., Sondek, J., & Der, C. J. (2001) · Nature Structural Biology

Protein Kinase Regulation and GTPase SignalingCellular transport and secretion

Cited by 93

The RalB Small GTPase Mediates Formation of Invadopodia through a GTPase-Activating Protein-Independent Function of the RalBP1/RLIP76 Effector

Neel, N. F., Rossman, K. L., Martin, T. D., Hayes, T. K., Yeh, J. J., & Der, C. J. (2012) · Molecular and Cellular Biology

Protein Kinase Regulation and GTPase SignalingCellular transport and secretion

Cited by 71

Auto-inhibition of the Dbl Family Protein Tim by an N-terminal Helical Motif

Yohe, M. E., Rossman, K. L., Gardner, O. S., Karnoub, A. E., Snyder, J. T., Gershburg, S., Graves, L. M., Der, C. J., & Sondek, J. (2007) · Journal of Biological Chemistry

Protein Kinase Regulation and GTPase SignalingCellular transport and secretion

Cited by 45