Lowes, Kym N.

Exploiting selective BCL-2 family inhibitors to dissect cell survival dependencies and define improved strategies for cancer therapy

Leverson, J. D., Phillips, D. C., Mitten, M. J., Boghaert, E. R., Diaz, D., Tahir, S. K., Belmont, L. D., Nimmer, P., Xiao, Y., Ma, X. M., et al. (2015) · Science Translational Medicine

Cell death mechanisms and regulationCancer-related Molecular Pathways

Cited by 541

HSP90 activity is required for MLKL oligomerisation and membrane translocation and the induction of necroptotic cell death

Jacobsen, A. V., Lowes, K. N., Tanzer, M. C., Lucet, I. S., Hildebrand, J. M., Petrie, E. J., van Delft, M. F., Liu, Z., Conos, S. A., Zhang, J.-G., et al. (2016) · Cell Death & Disease

Cell death mechanisms and regulationHeat shock proteins research

Cited by 160

Basis for drug selectivity of plasmepsin IX and X inhibition in Plasmodium falciparum and vivax

Hodder, A. N., Christensen, J., Scally, S., Triglia, T., Ngo, A., Birkinshaw, R. W., Bailey, B., Favuzza, P., Dietrich, M. H., Tham, W.-H., et al. (2022) · Structure

Malaria Research and ControlProtease and Inhibitor Mechanisms

Cited by 35