Wayment-Steele, Hannah K.

Predicting multiple conformations via sequence clustering and AlphaFold2

Wayment-Steele, H. K., Ojoawo, A., Otten, R., Apitz, J. M., Pitsawong, W., Hömberger, M., Ovchinnikov, S., Colwell, L., & Kern, D. (2024) · Nature

Protein Structure and DynamicsEnzyme Structure and Function

Cited by 545

Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics

Leppek, K., Byeon, G. W., Kladwang, W., Wayment-Steele, H. K., Kerr, C. H., Xu, A. F., Kim, D. S., Topkar, V. V., Choe, C., Rothschild, D., et al. (2021) · Nature Communications

RNA and protein synthesis mechanismsRNA Interference and Gene Delivery

Cited by 399

Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics

Leppek, K., Byeon, G. W., Kladwang, W., Wayment-Steele, H. K., Kerr, C. H., Xu, A. F., Kim, D. S., Topkar, V. V., Choe, C., Rothschild, D., et al. (2022) · Nature Communications

RNA and protein synthesis mechanismsRNA Interference and Gene Delivery

Cited by 399

Theoretical basis for stabilizing messenger RNA through secondary structure design

Wayment-Steele, H. K., Kim, D. S., Choe, C. A., Nicol, J. J., Wellington-Oguri, R., Watkins, A. M., Sperberg, R. A. P., Huang, P.-S., Participants, E., & Das, R. (2020) · Nucleic Acids Research

RNA and protein synthesis mechanismsRNA Research and Splicing

Cited by 199

Theoretical basis for stabilizing messenger RNA through secondary structure design

Wayment-Steele, H. K., Kim, D. S., Choe, C. A., Nicol, J. J., Wellington-Oguri, R., Watkins, A. M., Parra Sperberg, R. A., Huang, P.-S., Participants, E., & Das, R. (2021) · Nucleic Acids Research

RNA and protein synthesis mechanismsRNA Research and Splicing

Cited by 197

Protein language models learn evolutionary statistics of interacting sequence motifs

Zhang, Z., Wayment-Steele, H. K., Brixi, G., Wang, H., Kern, D., & Ovchinnikov, S. (2024) · Proceedings of the National Academy of Sciences

Protein Structure and DynamicsMachine Learning in Bioinformatics

Cited by 140

The conformational landscape of fold-switcher KaiB is tuned to the circadian rhythm timescale

Wayment-Steele, H. K., Otten, R., Pitsawong, W., Ojoawo, A. M., Glaser, A., Calderone, L. A., & Kern, D. (2024) · Proceedings of the National Academy of Sciences

Protein Structure and DynamicsCircadian rhythm and melatonin

Cited by 19

The conformational landscape of fold-switcher KaiB is tuned to the circadian rhythm timescale

Wayment-Steele, H. K., Otten, R., Pitsawong, W., Ojoawo, A. M., Glaser, A., Calderone, L. A., & Kern, D. (2024) · Proceedings of the National Academy of Sciences

Protein Structure and DynamicsCircadian rhythm and melatonin

Cited by 19

Does sequence clustering confound AlphaFold2?

Wayment-Steele, H. K., Ovchinnikov, S., Colwell, L., & Kern, D. (2024) · Journal of Molecular Biology

Protein Structure and DynamicsMachine Learning in Bioinformatics

Cited by 8