Zhan, Tianzuo

Wnt signaling in cancer

Zhan, T., Rindtorff, N., & Boutros, M. (2017) · Oncogene

Wnt/β-catenin signaling in development and cancerCancer Cells and Metastasis

Cited by 2,626

Pooled In Vitro and In Vivo CRISPR-Cas9 Screening Identifies Tumor Suppressors in Human Colon Organoids

Michels, B. E., Mosa, M. H., Streibl, B. I., Zhan, T., Menche, C., Abou-El-Ardat, K., Darvishi, T., Członka, E., Wagner, S., Winter, J., et al. (2020) · Cell Stem Cell

CRISPR and Genetic EngineeringChromatin Remodeling and Cancer

Cited by 222

MEK inhibitors activate Wnt signalling and induce stem cell plasticity in colorectal cancer

Zhan, T., Ambrosi, G., Wandmacher, A. M., Rauscher, B., Betge, J., Rindtorff, N., Häussler, R. S., Hinsenkamp, I., Bamberg, L., Hessling, B., et al. (2019) · Nature Communications

Wnt/β-catenin signaling in development and cancerCancer Cells and Metastasis

Cited by 189

Targeting the DNA Damage Response and DNA Repair Pathways to Enhance Radiosensitivity in Colorectal Cancer

Deng, S., Vlatkovic, T., Li, M., Zhan, T., Veldwijk, M. R., & Herskind, C. (2022) · Cancers

DNA Repair MechanismsPARP inhibition in cancer therapy

Cited by 62

A multicenter open-label phase II trial to evaluate nivolumab and ipilimumab for 2nd line therapy in elderly patients with advanced esophageal squamous cell cancer (RAMONA)

Meindl-Beinker, N. M., Betge, J., Gutting, T., Burgermeister, E., Belle, S., Zhan, T., Schulte, N., Maenz, M., Ebert, M. P., & Haertel, N. (2019) · BMC Cancer

Cancer Immunotherapy and BiomarkersEsophageal Cancer Research and Treatment

Cited by 30