Lazar, Mitchell A.

Dichotomous engagement of HDAC3 activity governs inflammatory responses

Nguyen, H. C. B., Adlanmerini, M., Hauck, A. K., & Lazar, M. A. (2020) · Nature

Histone Deacetylase Inhibitors ResearchGenomics and Chromatin Dynamics

Cited by 150

Thyroid hormone action: a binding contract

Lazar, M. A. (2003) · Journal of Clinical Investigation

Thyroid Disorders and TreatmentsEstrogen and related hormone effects

Cited by 143

Assembly of the SMRT–histone deacetylase 3 repression complex requires the TCP-1 ring complex

Guenther, M. G., Yu, J., Kao, G. D., Yen, T. J., & Lazar, M. A. (2002) · Genes & Development

Histone Deacetylase Inhibitors ResearchGenomics and Chromatin Dynamics

Cited by 138

Genetic Variation Determines PPARγ Function and Anti-diabetic Drug Response In Vivo

Soccio, R. E., Chen, E. R., Rajapurkar, S. R., Safabakhsh, P., Marinis, J. M., Dispirito, J. R., Emmett, M. J., Briggs, E. R., Fang, B., Everett, L. J., et al. (2015) · Cell

Peroxisome Proliferator-Activated ReceptorsGenetic Associations and Epidemiology

Cited by 117

ETO interacting proteins

Hug, B. A., & Lazar, M. A. (2004) · Oncogene

Acute Myeloid Leukemia ResearchGenomics and Chromatin Dynamics

Cited by 112

Dysregulation of a long noncoding RNA reduces leptin leading to a leptin-responsive form of obesity

Dallner, O. S., Marinis, J. M., Lu, Y.-H., Birsoy, K., Werner, E., Fayzikhodjaeva, G., Dill, B. D., Molina, H., Moscati, A., Kutalik, Z., et al. (2019) · Nature Medicine

Regulation of Appetite and ObesityAdipokines, Inflammation, and Metabolic Diseases

Cited by 106

The Transcriptional Integrator CREB-Binding Protein Mediates Positive Cross Talk between Nuclear Hormone Receptors and the Hematopoietic bZip Protein p45/NF-E2

Cheng, X., Reginato, M. J., Andrews, N. C., & Lazar, M. A. (1997) · Molecular and Cellular Biology

Retinoids in leukemia and cellular processesGenomics and Chromatin Dynamics

Cited by 102

Structural insights into the interaction and activation of histone deacetylase 3 by nuclear receptor corepressors

Codina, A., Love, J. D., Li, Y., Lazar, M. A., Neuhaus, D., & Schwabe, J. W. R. (2005) · Proceedings of the National Academy of Sciences

Histone Deacetylase Inhibitors ResearchGenomics and Chromatin Dynamics

Cited by 95

Immunocytochemical delineation of thyroid hormone receptor beta 2-like immunoreactivity in the rat central nervous system.

Lechan, R. M., Qi, Y., Berrodin, T. J., Davis, K. D., Schwartz, H. L., Strait, K. A., Oppenheimer, J. H., & Lazar, M. A. (1993) · Endocrinology

Thyroid Disorders and TreatmentsEstrogen and related hormone effects

Cited by 85

A novel adipose-specific gene deletion model demonstrates potential pitfalls of existing methods

Mullican, S. E., Tomaru, T., Gaddis, C. A., Peed, L. C., Sundaram, A., & Lazar, M. A. (2013) · Molecular Endocrinology

Adipose Tissue and MetabolismAdipokines, Inflammation, and Metabolic Diseases

Cited by 83

An HDAC3-PROX1 corepressor module acts on HNF4α to control hepatic triglycerides

Armour, S. M., Remsberg, J. R., Damle, M., Sidoli, S., Ho, W. Y., Li, Z., Garcia, B. A., & Lazar, M. A. (2017) · Nature Communications

Histone Deacetylase Inhibitors ResearchLiver Disease Diagnosis and Treatment

Cited by 69

Hepatocytes demarcated by EphB2 contribute to the progression of nonalcoholic steatohepatitis

Xiao, Y., Batmanov, K., Hu, W., Zhu, K., Tom, A. Y., Guan, D., Jiang, C., Cheng, L., McCright, S. J., Yang, E. C., et al. (2023) · Science Translational Medicine

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 69

The Interaction between Nuclear Receptor Corepressor and Histone Deacetylase 3 Regulates Both Positive and Negative Thyroid Hormone Action in Vivo

You, S.-H., Liao, X., Weiss, R. E., & Lazar, M. A. (2010) · Molecular Endocrinology

Thyroid Disorders and TreatmentsEstrogen and related hormone effects

Cited by 61

The Nuclear Receptor Corepressor Deacetylase Activating Domain Is Essential for Repression by Thyroid Hormone Receptor

Ishizuka, T., & Lazar, M. A. (2005) · Molecular Endocrinology

Estrogen and related hormone effectsGenomics and Chromatin Dynamics

Cited by 50

Stereospecificity of Retinol Saturase: Absolute Configuration, Synthesis, and Biological Evaluation of Dihydroretinoids

Moise, A. R., Domínguez, M., Alvarez, S., Alvarez, R., Schupp, M., Cristancho, A. G., Kiser, P. D., de Lera, A. R., Lazar, M. A., & Palczewski, K. (2008) · Journal of the American Chemical Society

Retinoids in leukemia and cellular processesPeroxisome Proliferator-Activated Receptors

Cited by 40