Lazar, Mitchell A.

The hormone resistin links obesity to diabetes

Steppan, C. M., Bailey, S. T., Bhat, S., Brown, E. J., Banerjee, R. R., Wright, C. M., Patel, H. R., Ahima, R. S., & Lazar, M. A. (2001) · Nature

Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and Metabolism

Cited by 4,755

Histone Deacetylase Is a Direct Target of Valproic Acid, a Potent Anticonvulsant, Mood Stabilizer, and Teratogen

Phiel, C. J., Zhang, F., Huang, E. Y., Guenther, M. G., Lazar, M. A., & Klein, P. S. (2001) · Journal of Biological Chemistry

Histone Deacetylase Inhibitors ResearchPharmacological Effects and Toxicity Studies

Cited by 1,758

Forming functional fat: a growing understanding of adipocyte differentiation

Cristancho, A. G., & Lazar, M. A. (2011) · Nature Reviews Molecular Cell Biology

Peroxisome Proliferator-Activated ReceptorsAdipose Tissue and Metabolism

Cited by 1,382

Lipid-associated macrophages control metabolic homeostasis in a Trem2-dependent manner

Jaitin, D. A., Adlung, L., Thaiss, C. A., Weiner, A., Li, B., Descamps, H., Lundgren, P., Bleriot, C., Liu, Z., Deczkowska, A., et al. (2019) · Cell

Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and Metabolism

Cited by 1,377

Enzymatic Activity Associated with Class II HDACs Is Dependent on a Multiprotein Complex Containing HDAC3 and SMRT/N-CoR

Fischle, W., Dequiedt, F., Hendzel, M. J., Guenther, M. G., Lazar, M. A., Voelter, W., & Verdin, E. (2002) · Molecular Cell

Histone Deacetylase Inhibitors ResearchGenomics and Chromatin Dynamics

Cited by 754

Rev-erbα, a Heme Sensor That Coordinates Metabolic and Circadian Pathways

Yin, L., Wu, N., Curtin, J. C., Qatanani, M., Szwergold, N. R., Reid, R. A., Waitt, G. M., Parks, D. J., Pearce, K. H., Wisely, G. B., et al. (2007) · Science

Circadian rhythm and melatoninNuclear Receptors and Signaling

Cited by 707

A circadian rhythm orchestrated by histone deacetylase 3 controls hepatic lipid metabolism

Feng, D., Liu, T., Sun, Z., Bugge, A., Mullican, S. E., Alenghat, T., Liu, X. S., & Lazar, M. A. (2011) · Science

Circadian rhythm and melatoninHistone Deacetylase Inhibitors Research

Cited by 701

Mitochondrial remodeling in adipose tissue associated with obesity and treatment with rosiglitazone.

Wilson-Fritch, L., Nicoloro, S., Chouinard, M., Lazar, M. A., Chui, P. C., Leszyk, J., Straubhaar, J., Czech, M. P., & Corvera, S. (2004) · Journal of Clinical Investigation

Adipose Tissue and MetabolismPeroxisome Proliferator-Activated Receptors

Cited by 616

The SMRT and N-CoR Corepressors Are Activating Cofactors for Histone Deacetylase 3

Guenther, M. G., Barak, O., & Lazar, M. A. (2001) · Molecular and Cellular Biology

Histone Deacetylase Inhibitors ResearchGenomics and Chromatin Dynamics

Cited by 611

Regeneration of fat cells from myofibroblasts during wound healing

Plikus, M. V., Guerrero-Juarez, C. F., Ito, M., Li, Y. R., Dedhia, P. H., Zheng, Y., Shao, M., Gay, D. L., Ramos, R., Hsi, T.-C., et al. (2017) · Science

Wound Healing and TreatmentsHair Growth and Disorders

Cited by 584

Thiazolidinediones and the promise of insulin sensitization in type 2 diabetes

Soccio, R. E., Chen, E. R., & Lazar, M. A. (2014) · Cell Metabolism

Peroxisome Proliferator-Activated ReceptorsDiabetes Treatment and Management

Cited by 518

HDAC3 Is a Critical Negative Regulator of Long-Term Memory Formation

McQuown, S. C., Barrett, R. M., Matheos, D. P., Post, R. J., Rogge, G. A., Alenghat, T., Mullican, S. E., Jones, S., Rusche, J. R., Lazar, M. A., et al. (2011) · The Journal of Neuroscience

Memory and Neural MechanismsHistone Deacetylase Inhibitors Research

Cited by 507

International Union of Pharmacology. LXIII. Retinoid X receptors

Germain, P., Chambon, P., Eichele, G., Evans, R. M., Lazar, M. A., Leid, M., De Lera, A. R., Lotan, R., Mangelsdorf, D. J., & Gronemeyer, H. (2006) · Pharmacological Reviews

Retinoids in leukemia and cellular processesPeroxisome Proliferator-Activated Receptors

Cited by 496

A core SMRT corepressor complex containing HDAC3 and TBL1, a WD40-repeat protein linked to deafness

Guenther, M. G., Lane, W. S., Fischle, W., Verdin, E., Lazar, M. A., & Shiekhattar, R. (2000) · Genes & Development

Genomics and Chromatin DynamicsHistone Deacetylase Inhibitors Research

Cited by 489

Regulation of the brown and white fat gene programs through a PRDM16/CtBP transcriptional complex

Kajimura, S., Seale, P., Tomaru, T., Erdjument-Bromage, H., Cooper, M. P., Ruas, J. L., Chin, S., Tempst, P., Lazar, M. A., & Spiegelman, B. M. (2008) · Genes & Development

Adipose Tissue and MetabolismPeroxisome Proliferator-Activated Receptors

Cited by 468

Distinct macrophage populations direct inflammatory versus physiological changes in adipose tissue

Hill, D. A., Lim, H.-W., Kim, Y. H., Ho, W. Y., Foong, Y. H., Nelson, V. L., Nguyen, H. C. B., Chegireddy, K., Kim, J., Habertheuer, A., et al. (2018) · Proceedings of the National Academy of Sciences

Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and Metabolism

Cited by 415

Hepatic Hdac3 promotes gluconeogenesis by repressing lipid synthesis and sequestration

Sun, Z., Miller, R. A., Patel, R. T., Chen, J., Dhir, R., Wang, H., Zhang, D., Graham, M. J., Unterman, T. G., Shulman, G. I., et al. (2012) · Nature Medicine

Liver Disease Diagnosis and TreatmentLipid metabolism and biosynthesis

Cited by 335

Histone deacetylase 3 is an epigenomic brake in macrophage alternative activation

Mullican, S. E., Gaddis, C. A., Alenghat, T., Nair, M. G., Giacomin, P. R., Everett, L. J., Feng, D., Steger, D. J., Schug, J., Artis, D., et al. (2011) · Genes & Development

Immune cells in cancerHistone Deacetylase Inhibitors Research

Cited by 314

Thyroid hormone stimulates hepatic lipid catabolism via activation of autophagy

Sinha, R. A., You, S.-H., Zhou, J., Siddique, M. M., Bay, B.-H., Zhu, X., Privalsky, M. L., Cheng, S.-Y., Stevens, R. D., Summers, S. A., et al. (2012) · Journal of Clinical Investigation

Autophagy in Disease and TherapyThyroid Disorders and Treatments

Cited by 303

Retinoic Acid Blocks Adipogenesis by Inhibiting C/EBPβ-Mediated Transcription

Schwarz, E. J., Reginato, M. J., Shao, D., Krakow, S. L., & Lazar, M. A. (1997) · Molecular and Cellular Biology

Peroxisome Proliferator-Activated ReceptorsAdipose Tissue and Metabolism

Cited by 302

Human resistin: found in translation from mouse to man

Schwartz, D. R., & Lazar, M. A. (2011) · Trends in Endocrinology & Metabolism

Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and Metabolism

Cited by 297

Clocks, metabolism, and the epigenome

Feng, D., & Lazar, M. A. (2012) · Molecular Cell

Circadian rhythm and melatoninEpigenetics and DNA Methylation

Cited by 271

Integrative regulation of physiology by histone deacetylase 3

Emmett, M. J., & Lazar, M. A. (2019) · Nature Reviews Molecular Cell Biology

Histone Deacetylase Inhibitors ResearchGenomics and Chromatin Dynamics

Cited by 202

Circadian metabolism in the light of evolution

Gerhart-Hines, Z., & Lazar, M. A. (2015) · Endocrine Reviews

Circadian rhythm and melatoninSleep and Work-Related Fatigue

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