Newton, Kim

Cryopyrin activates the inflammasome in response to toxins and ATP

Mariathasan, S., Weiss, D. S., Newton, K., McBride, J., O'Rourke, K., Roose-Girma, M., Lee, W. P., Weinrauch, Y., Monack, D. M., & Dixit, V. M. (2006) · Nature

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 3,080

Non-canonical inflammasome activation targets caspase-11

Kayagaki, N., Warming, S., Lamkanfi, M., Walle, L. V., Louie, S., Dong, J., Newton, K., Qu, Y., Liu, J., Heldens, S., et al. (2011) · Nature

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 2,530

Signaling in innate immunity and inflammation

Newton, K., & Dixit, V. M. (2012) · Cold Spring Harbor Perspectives in Biology

Immune Response and InflammationNF-κB Signaling Pathways

Cited by 1,513

Activity of Protein Kinase RIPK3 Determines Whether Cells Die by Necroptosis or Apoptosis

Newton, K., Dugger, D. L., Wickliffe, K. E., Kapoor, N., de Almagro, M. C., Vucic, D., Komuves, L., Ferrando, R. E., French, D. M., Webster, J., et al. (2014) · Science

Cell death mechanisms and regulationNF-κB Signaling Pathways

Cited by 687

Redundant roles for inflammasome receptors NLRP3 and NLRC4 in host defense against Salmonella

Broz, P., Newton, K., Lamkanfi, M., Mariathasan, S., Dixit, V. M., & Monack, D. M. (2010) · Journal of Experimental Medicine

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 549

RIPK1 inhibits ZBP1-driven necroptosis during development

Newton, K., Wickliffe, K. E., Maltzman, A., Dugger, D. L., Strasser, A., Pham, V. C., Lill, J. R., Roose-Girma, M., Warming, S., Solon, M., et al. (2016) · Nature

Cell death mechanisms and regulationNF-κB Signaling Pathways

Cited by 390

Selective activation of PFKL suppresses the phagocytic oxidative burst

Amara, N., Cooper, M. P., Voronkova, M. A., Webb, B. A., Lynch, E. M., Kollman, J. M., Ma, T., Yu, K., Lai, Z., Sangaraju, D., et al. (2021) · Cell

Neutrophil, Myeloperoxidase and Oxidative MechanismsRedox biology and oxidative stress

Cited by 158

JNK-mediated phosphorylation of DLK suppresses its ubiquitination to promote neuronal apoptosis

Huntwork-Rodriguez, S., Wang, B., Watkins, T., Ghosh, A. S., Pozniak, C. D., Bustos, D., Newton, K., Kirkpatrick, D. S., & Lewcock, J. W. (2013) · Journal of Cell Biology

Ubiquitin and proteasome pathwaysNerve injury and regeneration

Cited by 154

The RIPK4–IRF6 signalling axis safeguards epidermal differentiation and barrier function

Oberbeck, N., Pham, V. C., Webster, J. D., Reja, R., Huang, C. S., Zhang, Y., Roose-Girma, M., Warming, S., Li, Q., Birnberg, A., et al. (2019) · Nature

Skin and Cellular Biology ResearchGenetic and rare skin diseases.

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