Greenberg, Roger A.
University of Pennsylvania
15 papers on CoChatORCID 0000-0003-1326-8981
Most cited papers
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Mitotic progression following DNA damage enables pattern recognition within micronuclei
Harding, S. M., Benci, J. L., Irianto, J., Discher, D. E., Minn, A. J., & Greenberg, R. A. (2017) · Nature
interferon and immune responsesDNA Repair Mechanisms
Cited by 1,508
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ATM-Dependent Chromatin Changes Silence Transcription In cis to DNA Double-Strand Breaks
Shanbhag, N. M., Rafalska-Metcalf, I. U., Balane-Bolivar, C., Janicki, S. M., & Greenberg, R. A. (2010) · Cell
DNA Repair MechanismsGenomics and Chromatin Dynamics
Cited by 737
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Acetylation limits 53BP1 association with damaged chromatin to promote homologous recombination
Tang, J., Cho, N. W., Cui, G., Manion, E. M., Shanbhag, N. M., Botuyan, M. V., Mer, G., & Greenberg, R. A. (2013) · Nature Structural & Molecular Biology
DNA Repair MechanismsPARP inhibition in cancer therapy
Cited by 521
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HIF-α effects on c-Myc distinguish two subtypes of sporadic VHL-deficient clear cell renal carcinoma
Gordan, J. D., Lal, P., Dondeti, V. R., Letrero, R., Parekh, K. N., Oquendo, C. E., Greenberg, R. A., Flaherty, K. T., Rathmell, W. K., Keith, B., et al. (2008) · Cancer Cell
Cancer, Hypoxia, and MetabolismRenal cell carcinoma treatment
Cited by 493
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Short Dysfunctional Telomeres Impair Tumorigenesis in the INK4aΔ2/3 Cancer-Prone Mouse
Greenberg, R. A., Chin, L., Femino, A., Lee, K.-H., Gottlieb, G. J., Singer, R. H., Greider, C. W., & DePinho, R. A. (1999) · Cell
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 367
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Constitutive telomerase expression promotes mammary carcinomas in aging mice
Artandi, S. E., Alson, S., Tietze, M. K., Sharpless, N. E., Ye, S., Greenberg, R. A., Castrillon, D. H., Horner, J. W., Weiler, S. R., Carrasco, R. D., et al. (2002) · Proceedings of the National Academy of Sciences
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 317
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Multifactorial contributions to an acute DNA damage response by BRCA1/BARD1-containing complexes
Greenberg, R. A., Sobhian, B., Pathania, S., Cantor, S. B., Nakatani, Y., & Livingston, D. M. (2006) · Genes & Development
DNA Repair MechanismsBRCA gene mutations in cancer
Cited by 308
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Nuclear Acetyl-CoA Production by ACLY Promotes Homologous Recombination
Sivanand, S., Rhoades, S., Jiang, Q., Lee, J. V., Benci, J., Zhang, J., Yuan, S., Viney, I., Zhao, S., Carrer, A., et al. (2017) · Molecular Cell
DNA Repair MechanismsPARP inhibition in cancer therapy
Cited by 295
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DNA damage-induced type I interferon promotes senescence and inhibits stem cell function
Yu, Q., Katlinskaya, Y. V., Carbone, C. J., Zhao, B., Katlinski, K. V., Zheng, H., Guha, M., Li, N., Chen, Q., Yang, T., et al. (2015) · Cell Reports
interferon and immune responsesTelomeres, Telomerase, and Senescence
Cited by 260
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Cell cycle checkpoints cooperate to suppress DNA- and RNA-associated molecular pattern recognition and anti-tumor immune responses
Chen, J., Harding, S. M., Natesan, R., Tian, L., Benci, J. L., Li, W., Minn, A. J., Asangani, I. A., & Greenberg, R. A. (2020) · Cell Reports
interferon and immune responsesImmune Response and Inflammation
Cited by 111
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A BRISC-SHMT Complex Deubiquitinates IFNAR1 and Regulates Interferon Responses
Zheng, H., Gupta, V., Patterson-Fortin, J., Bhattacharya, S., Katlinski, K., Wu, J., Varghese, B., Carbone, C. J., Aressy, B., Fuchs, S. Y., et al. (2013) · Cell Reports
Ubiquitin and proteasome pathwaysinterferon and immune responses
Cited by 101
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Differential regulation of JAMM domain deubiquitinating enzyme activity within the RAP80 complex
Patterson-Fortin, J., Shao, G., Bretscher, H., Messick, T. E., & Greenberg, R. A. (2010) · Journal of Biological Chemistry
Ubiquitin and proteasome pathwaysDNA Repair Mechanisms
Cited by 85
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Metabolic control of BRISC-SHMT2 assembly regulates immune signalling
Walden, M., Tian, L., Ross, R. L., Sykora, U. M., Byrne, D. P., Hesketh, E. L., Masandi, S. K., Cassel, J., George, R., Ault, J. R., et al. (2019) · Nature
Ubiquitin and proteasome pathwaysEnzyme Structure and Function
Cited by 85
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Breast Cancer–Associated Abraxas Mutation Disrupts Nuclear Localization and DNA Damage Response Functions
Solyom, S., Aressy, B., Pylkäs, K., Patterson-Fortin, J., Hartikainen, J. M., Kallioniemi, A., Kauppila, S., Nikkilä, J., Kosma, V.-M., Mannermaa, A., et al. (2012) · Science Translational Medicine
BRCA gene mutations in cancerDNA Repair Mechanisms
Cited by 59
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CHAMP1 complex directs heterochromatin assembly and promotes homology-directed DNA repair
Li, F., Zhang, T., Syed, A., Elbakry, A., Holmer, N., Nguyen, H., Mukkavalli, S., Greenberg, R. A., & D’Andrea, A. D. (2025) · Nature Communications
DNA Repair MechanismsGenomics and Chromatin Dynamics
Cited by 13
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