Calkins, David J.

Distal axonopathy with structural persistence in glaucomatous neurodegeneration

Crish, S. D., Sappington, R. M., Inman, D. M., Horner, P. J., & Calkins, D. J. (2010) · Proceedings of the National Academy of Sciences

Glaucoma and retinal disordersNerve injury and regeneration

Cited by 350

Solving neurodegeneration: common mechanisms and strategies for new treatments

Wareham, L. K., Liddelow, S. A., Temple, S., Benowitz, L. I., Di Polo, A., Wellington, C., Goldberg, J. L., He, Z., Duan, X., Bu, G., et al. (2022) · Molecular Neurodegeneration

Glaucoma and retinal disordersNeuroinflammation and Neurodegeneration Mechanisms

Cited by 324

Bilateral visual improvement with unilateral gene therapy injection for Leber hereditary optic neuropathy

Yu-Wai-Man, P., Newman, N. J., Carelli, V., Moster, M. L., Biousse, V., Sadun, A. A., Klopstock, T., Vignal-Clermont, C., Sergott, R. C., Rudolph, G., et al. (2020) · Science Translational Medicine

Retinal Development and DisordersVirus-based gene therapy research

Cited by 232

Microarray analysis of retinal gene expression in the DBA/2J model of glaucoma

Steele, M. R., Inman, D. M., Calkins, D. J., Horner, P. J., & Vetter, M. L. (2006) · Investigative Opthalmology & Visual Science

Glaucoma and retinal disordersRetinal Diseases and Treatments

Cited by 196

Age-related changes in the visual pathways: blame it on the axon

Calkins, D. J. (2013) · Investigative Opthalmology & Visual Science

Glaucoma and retinal disordersRetinal Development and Disorders

Cited by 96

Proximal inhibition of p38 MAPK stress signaling prevents distal axonopathy

Dapper, J. D., Crish, S. D., Pang, I.-H., & Calkins, D. J. (2013) · Neurobiology of Disease

Glaucoma and retinal disordersConnexins and lens biology

Cited by 76

Biodistribution of intravitreal lenadogene nolparvovec gene therapy in nonhuman primates

Calkins, D. J., Yu-Wai-Man, P., Newman, N. J., Taiel, M., Singh, P., Chalmey, C., Rogue, A., Carelli, V., Ancian, P., & Sahel, J. A. (2021) · Molecular Therapy - Methods & Clinical Development

Virus-based gene therapy researchRetinal Development and Disorders

Cited by 37

Oral Delivery of a Synthetic Sterol Reduces Axonopathy and Inflammation in a Rodent Model of Glaucoma

Lambert, W. S., Carlson, B. J., Formichella, C. R., Sappington, R. M., Ahlem, C., & Calkins, D. J. (2017) · Frontiers in Neuroscience

Glaucoma and retinal disordersDrug-Induced Ocular Toxicity

Cited by 31

Of Mice and Monkeys: Neuroprotective Efficacy of the p38 Inhibitor BIRB 796 Depends on Model Duration in Experimental Glaucoma

Lambert, W. S., Pasini, S., Collyer, J. W., Formichella, C. R., Ghose, P., Carlson, B. J., & Calkins, D. J. (2020) · Scientific Reports

Glaucoma and retinal disordersNeuroprotection in Cerebral Ischemia

Cited by 21