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Multiorgan and Renal Tropism of SARS-CoV-2

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Decoding myofibroblast origins in human kidney fibrosis

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Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging mice

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Role of mTOR in podocyte function and diabetic nephropathy in humans and mice

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mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice

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Endothelial cell and podocyte autophagy synergistically protect from diabetes-induced glomerulosclerosis

Lenoir, O., Jasiek, M., Hénique, C., Guyonnet, L., Hartleben, B., Bork, T., Chipont, A., Flosseau, K., Bensaada, I., Schmitt, A., et al. (2015) · Autophagy

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Cellular and Molecular Probing of Intact Human Organs

Zhao, S., Todorov, M. I., Cai, R., -Maskari, R. A., Steinke, H., Kemter, E., Mai, H., Rong, Z., Warmer, M., Stanic, K., et al. (2020) · Cell

Advanced Fluorescence Microscopy TechniquesSingle-cell and spatial transcriptomics

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Autophagy plays a critical role in kidney tubule maintenance, aging and ischemia-reperfusion injury

Liu, S., Hartleben, B., Kretz, O., Wiech, T., Igarashi, P., Mizushima, N., Walz, G., & Huber, T. B. (2012) · Autophagy

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The podocyte slit diaphragm--from a thin grey line to a complex signalling hub

Grahammer, F., Schell, C., & Huber, T. B. (2013) · Nature Reviews Nephrology

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Microbiota-Induced Type I Interferons Instruct a Poised Basal State of Dendritic Cells

Schaupp, L., Muth, S., Rogell, L., Kofoed-Branzk, M., Melchior, F., Lienenklaus, S., Ganal-Vonarburg, S. C., Klein, M., Guendel, F., Hain, T., et al. (2020) · Cell

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SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids

Jansen, J., Reimer, K. C., Nagai, J. S., Varghese, F. S., Overheul, G. J., de Beer, M., Roverts, R., Daviran, D., Fermin, L. A. S., Willemsen, B., et al. (2022) · Cell Stem Cell

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Roles of mTOR complexes in the kidney: implications for renal disease and transplantation

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Scribble participates in Hippo signaling and is required for normal zebrafish pronephros development

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Molecular fingerprinting of the podocyte reveals novel gene and protein regulatory networks

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Vps34 Deficiency Reveals the Importance of Endocytosis for Podocyte Homeostasis

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Persistent somatic symptoms across diseases - from risk factors to modification: scientific framework and overarching protocol of the interdisciplinary SOMACROSS research unit (RU 5211)

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mTORC1 maintains renal tubular homeostasis and is essential in response to ischemic stress

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A Multi-layered Quantitative In Vivo Expression Atlas of the Podocyte Unravels Kidney Disease Candidate Genes

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Loss of Podocyte aPKCλ/ι Causes Polarity Defects and Nephrotic Syndrome

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Podocytes maintain high basal levels of autophagy independent of mtor signaling

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The Potential of Semaglutide Once-Weekly in Patients Without Type 2 Diabetes with Weight Regain or Insufficient Weight Loss After Bariatric Surgery—a Retrospective Analysis

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Targeting mTOR Signaling Can Prevent the Progression of FSGS

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