Hopkins, Andrew L.

Network pharmacology: the next paradigm in drug discovery

Hopkins, A. L. (2008) · Nature Chemical Biology

Computational Drug Discovery MethodsBioinformatics and Genomic Networks

Cited by 4,622

How many drug targets are there?

Overington, J. P., Al-Lazikani, B., & Hopkins, A. L. (2006) · Nature Reviews Drug Discovery

Computational Drug Discovery MethodsPharmaceutical Economics and Policy

Cited by 3,505

The druggable genome

Hopkins, A. L., & Groom, C. R. (2002) · Nature Reviews Drug Discovery

Computational Drug Discovery MethodsPharmacogenetics and Drug Metabolism

Cited by 3,305

The role of ligand efficiency metrics in drug discovery

Hopkins, A. L., Keserü, G. M., Leeson, P. D., Rees, D. C., & Reynolds, C. H. (2014) · Nature Reviews Drug Discovery

Computational Drug Discovery MethodsChemical Synthesis and Analysis

Cited by 1,181

Automated design of ligands to polypharmacological profiles

Besnard, J., Ruda, G. F., Setola, V., Abecassis, K., Rodriguiz, R. M., Huang, X.-P., Norval, S., Sassano, M. F., Shin, A. I., Webster, L. A., et al. (2012) · Nature

Computational Drug Discovery MethodsCholinesterase and Neurodegenerative Diseases

Cited by 832

Can we rationally design promiscuous drugs?

HOPKINS, A., MASON, J., & OVERINGTON, J. (2006) · Current Opinion in Structural Biology

Computational Drug Discovery MethodsProtein Degradation and Inhibitors

Cited by 469