Simpkin, Adam J.

High‐accuracy protein structure prediction in CASP14

Pereira, J., Simpkin, A. J., Hartmann, M. D., Rigden, D. J., Keegan, R. M., & Lupas, A. N. (2021) · Proteins: Structure, Function, and Bioinformatics

Protein Structure and DynamicsEnzyme Structure and Function

Cited by 314

Assessment of three‐dimensional RNA structure prediction in CASP15

Das, R., Kretsch, R. C., Simpkin, A. J., Mulvaney, T., Pham, P., Rangan, R., Bu, F., Keegan, R. M., Topf, M., Rigden, D. J., et al. (2023) · Proteins: Structure, Function, and Bioinformatics

RNA and protein synthesis mechanismsProtein Structure and Dynamics

Cited by 139

Assessing the utility of CASP14 models for molecular replacement

Millán, C., Keegan, R. M., Pereira, J., Sammito, M. D., Simpkin, A. J., McCoy, A. J., Lupas, A. N., Hartmann, M. D., Rigden, D. J., & Read, R. J. (2021) · Proteins: Structure, Function, and Bioinformatics

Enzyme Structure and FunctionProtein Structure and Dynamics

Cited by 62

Evaluation of model refinement in CASP14

Simpkin, A. J., Sánchez Rodríguez, F., Mesdaghi, S., Kryshtafovych, A., & Rigden, D. J. (2021) · Proteins: Structure, Function, and Bioinformatics

Protein Structure and DynamicsEnzyme Structure and Function

Cited by 28

AlphaFold 2, but not AlphaFold 3, predicts confident but unrealistic β-solenoid structures for repeat proteins

Pratt, O. S., Elliott, L. G., Haon, M., Mesdaghi, S., Price, R. M., Simpkin, A. J., & Rigden, D. J. (2024) · Computational and Structural Biotechnology Journal

Protein Structure and DynamicsEnzyme Structure and Function

Cited by 27

AlphaFold 2, but not AlphaFold 3, predicts confident but unrealistic β-solenoid structures for repeat proteins

Pratt, O. S., Elliott, L. G., Haon, M., Mesdaghi, S., Price, R. M., Simpkin, A. J., & Rigden, D. J. (2025) · Computational and Structural Biotechnology Journal

Protein Structure and DynamicsEnzyme Structure and Function

Cited by 27

MrParse : finding homologues in the PDB and the EBI AlphaFold database for molecular replacement and more

Simpkin, A. J., Thomas, J. M. H., Keegan, R. M., & Rigden, D. J. (2022) · Acta Crystallographica Section D Structural Biology

Enzyme Structure and FunctionProtein Structure and Dynamics

Cited by 24

Structural insights into pink-eyed dilution protein (Oca2)

Mesdaghi, S., Murphy, D. L., Simpkin, A. J., & Rigden, D. J. (2023) · Bioscience Reports

Protein Structure and Dynamicsmelanin and skin pigmentation

Cited by 13

ABCFold: easier running and comparison of AlphaFold 3, Boltz-1, and Chai-1

Elliott, L. G., Simpkin, A. J., & Rigden, D. J. (2024) · Bioinformatics Advances

Protein Structure and DynamicsMachine Learning in Bioinformatics

Cited by 12

ABCFold: easier running and comparison of AlphaFold 3, Boltz-1 and Chai-1

Elliott, L. G., Simpkin, A. J., & Rigden, D. J. (2025) · Bioinformatics Advances

Protein Structure and DynamicsMachine Learning in Bioinformatics

Cited by 12