Reher, Raphael

Systematic classification of unknown metabolites using high-resolution fragmentation mass spectra

Dührkop, K., Nothias, L.-F., Fleischauer, M., Reher, R., Ludwig, M., Hoffmann, M. A., Petras, D., Gerwick, W. H., Rousu, J., Dorrestein, P. C., et al. (2021) · Nature Biotechnology

Metabolomics and Mass Spectrometry StudiesMass Spectrometry Techniques and Applications

Cited by 860

NPClassifier: A Deep Neural Network-Based Structural Classification Tool for Natural Products

Kim, H. W., Wang, M., Leber, C. A., Nothias, L.-F., Reher, R., Kang, K. B., van der Hooft, J. J. J., Dorrestein, P. C., Gerwick, W. H., & Cottrell, G. W. (2021) · Journal of Natural Products

Computational Drug Discovery MethodsMicrobial Natural Products and Biosynthesis

Cited by 551

Design of Gallinamide A Analogs as Potent Inhibitors of the Cysteine Proteases Human Cathepsin L and Trypanosoma cruzi Cruzain

Boudreau, P. D., Miller, B. W., McCall, L.-I., Almaliti, J., Reher, R., Hirata, K., Le, T., Siqueira-Neto, J. L., Hook, V., & Gerwick, W. H. (2019) · Journal of Medicinal Chemistry

Protease and Inhibitor MechanismsTrypanosoma species research and implications

Cited by 57

Native metabolomics identifies the rivulariapeptolide family of protease inhibitors

Reher, R., Aron, A. T., Fajtová, P., Stincone, P., Wagner, B., Pérez-Lorente, A. I., Liu, C., Shalom, I. Y. B., Bittremieux, W., Wang, M., et al. (2022) · Nature Communications

Microbial Natural Products and BiosynthesisMetabolomics and Mass Spectrometry Studies

Cited by 53

NPOmix: a machine learning classifier to connect mass spectrometry fragmentation data to biosynthetic gene clusters

Leão, T. F., Wang, M., da Silva, R., Gurevich, A., Bauermeister, A., Gomes, P. W. P., Brejnrod, A., Glukhov, E., Aron, A. T., Louwen, J. J. R., et al. (2021) · PNAS Nexus

Microbial Natural Products and BiosynthesisMetabolomics and Mass Spectrometry Studies

Cited by 32

Native Metabolomics Unveils Suomilide Analogs with Potent Trypsin Inhibitory Activity

Naimi, A., Ulbricht, C., Trinh, T. L., Kehraus, S., Dreckmann, T. M., Linne, U., Hardes, K., Reher, R., & Baunach, M. (2026) · Journal of Natural Products

Microbial Natural Products and BiosynthesisBioactive natural compounds

Cited by 1