Holzhütter, Hermann-Georg

Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME

Godoy, P., Hewitt, N. J., Albrecht, U., Andersen, M. E., Ansari, N., Bhattacharya, S., Bode, J. G., Bolleyn, J., Borner, C., Böttger, J., et al. (2013) · Archives of Toxicology

Drug-Induced Hepatotoxicity and ProtectionLiver physiology and pathology

Cited by 1,280

Quantifying the Contribution of the Liver to Glucose Homeostasis: A Detailed Kinetic Model of Human Hepatic Glucose Metabolism

König, M., Bulik, S., & Holzhütter, H.-G. (2012) · PLoS Computational Biology

Metabolism, Diabetes, and CancerPancreatic function and diabetes

Cited by 202

Oxygen Consumption Rates during Three Different Neuronal Activity States in the Hippocampal CA3 Network

Huchzermeyer, C., Berndt, N., Holzhütter, H.-G., & Kann, O. (2013) · Journal of Cerebral Blood Flow & Metabolism

Neural dynamics and brain functionNeuroscience and Neuropharmacology Research

Cited by 81

Physiology-based kinetic modeling of neuronal energy metabolism unravels the molecular basis of NAD(P)H fluorescence transients

Berndt, N., Kann, O., & Holzhütter, H.-G. (2015) · Journal of Cerebral Blood Flow & Metabolism

Mitochondrial Function and PathologyAdvanced Fluorescence Microscopy Techniques

Cited by 56

The relative importance of kinetic mechanisms and variable enzyme abundances for the regulation of hepatic glucose metabolism – insights from mathematical modeling

Bulik, S., Holzhütter, H.-G., & Berndt, N. (2016) · BMC Biology

Metabolism, Diabetes, and CancerGene Regulatory Network Analysis

Cited by 45