Saville, Mark K

p53 isoforms can regulate p53 transcriptional activity

Bourdon, J.-C., Fernandes, K., Murray-Zmijewski, F., Liu, G., Diot, A., Xirodimas, D. P., Saville, M. K., & Lane, D. P. (2005) · Genes & Development

Cancer-related Molecular PathwaysCell death mechanisms and regulation

Cited by 810

Mdm2-Mediated NEDD8 Conjugation of p53 Inhibits Its Transcriptional Activity

Xirodimas, D. P., Saville, M. K., Bourdon, J.-C., Hay, R. T., & Lane, D. P. (2004) · Cell

Ubiquitin and proteasome pathwaysCancer-related Molecular Pathways

Cited by 570

The deubiquitinating enzyme USP2a regulates the p53 pathway by targeting Mdm2

Stevenson, L. F., Sparks, A., Allende‐Vega, N., Xirodimas, D. P., Lane, D. P., & Saville, M. K. (2007) · The EMBO Journal

Ubiquitin and proteasome pathwaysCancer-related Molecular Pathways

Cited by 280

Mdmx stabilizes p53 and Mdm2 via two distinct mechanisms

Stad, R., Little, N. A., Xirodimas, D. P., Frenk, R., van der Eb, A. J., Lane, D. P., Saville, M. K., & Jochemsen, A. G. (2001) · The EMBO Reports

Cancer-related Molecular PathwaysUbiquitin and proteasome pathways

Cited by 234

Different effects of p14ARF on the levels of ubiquitinated p53 and Mdm2 in vivo

Xirodimas, D., Saville, M. K., Edling, C., Lane, D. P., & Laín, S. (2001) · Oncogene

Cancer-related Molecular PathwaysUbiquitin and proteasome pathways

Cited by 169

Regulation of p53 by the Ubiquitin-conjugating Enzymes UbcH5B/C in Vivo

Saville, M. K., Sparks, A., Xirodimas, D. P., Wardrop, J., Stevenson, L. F., Bourdon, J.-C., Woods, Y. L., & Lane, D. P. (2004) · Journal of Biological Chemistry

Cancer-related Molecular PathwaysUbiquitin and proteasome pathways

Cited by 158

MdmX is a substrate for the deubiquitinating enzyme USP2a

Allende-Vega, N., Sparks, A., Lane, D. P., & Saville, M. K. (2010) · Oncogene

Ubiquitin and proteasome pathwaysCancer-related Molecular Pathways

Cited by 100