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The nucleolus directly regulates p53 export and degradation

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Cancer-mutated ribosome protein L22 (RPL22/eL22) suppresses cancer cell survival by blocking p53-MDM2 circuit

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The nucleoprotein of influenza A virus induces p53 signaling and apoptosis via attenuation of host ubiquitin ligase RNF43

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SAG/ROC2/Rbx2 Is a Novel Activator Protein-1 Target that Promotes c-Jun Degradation and Inhibits 12-O-Tetradecanoylphorbol-13-Acetate–Induced Neoplastic Transformation

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p14 Arf Promotes Small Ubiquitin-like Modifier Conjugation of Werners Helicase

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Nucleotide Binding by the MDM2 RING Domain Facilitates Arf-Independent MDM2 Nucleolar Localization

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The NEDD8 inhibitor MLN4924 increases the size of the nucleolus and activates p53 through the ribosomal-Mdm2 pathway

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MDM2 Mediates p300/CREB-binding Protein-associated Factor Ubiquitination and Degradation

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HDMX-L Is Expressed from a Functional p53-responsive Promoter in the First Intron of the HDMX Gene and Participates in an Autoregulatory Feedback Loop to Control p53 Activity

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UV Induces p21 Rapid Turnover Independently of Ubiquitin and Skp2

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Stability of nucleolar versus non-nucleolar forms of human p14ARF

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Targeting the ubiquitin–proteasome system to activate wild-type p53 for cancer therapy

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Modulation of p53 Cellular Function and Cell Death by African Swine Fever Virus

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The Xeroderma Pigmentosum Group E Gene Product DDB2 Activates Nucleotide Excision Repair by Regulating the Level of p21Waf1/Cip1

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E3 Ubiquitin Ligase RNF31 Cooperates with DAX-1 in Transcriptional Repression of Steroidogenesis

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Aberrant RNA methylation triggers recruitment of an alkylation repair complex

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Stabilization of p53 in Influenza A Virus-infected Cells Is Associated with Compromised MDM2-mediated Ubiquitination of p53

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The Balance between Mono- and NEDD8-Chains Controlled by NEDP1 upon DNA Damage Is a Regulatory Module of the HSP70 ATPase Activity

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Lack of Fetuin-A (α2-HS-Glycoprotein) Reduces Mammary Tumor Incidence and Prolongs Tumor Latency via the Transforming Growth Factor-β Signaling Pathway in a Mouse Model of Breast Cancer

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TRIM65 negatively regulates p53 through ubiquitination

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E3 Ligase cIAP2 Mediates Downregulation of MRE11 and Radiosensitization in Response to HDAC Inhibition in Bladder Cancer

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Modulation of p53 C-Terminal Acetylation by mdm2, p14ARF, and Cytoplasmic SirT2

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MDM2 interacts with and downregulates a sarcomeric protein, TCAP

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Small molecules that bind the Mdm2 RING stabilize and activate p53

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MAGE-A Cancer/Testis Antigens Inhibit MDM2 Ubiquitylation Function and Promote Increased Levels of MDM4

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Regulation of p53 in embryonic stem cells

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PRMT3 inhibits ubiquitination of ribosomal protein S2 and together forms an active enzyme complex

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A role for Numb in p53 stabilization

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ARF-BP1 as a potential therapeutic target

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Differences in the ubiquitination of p53 by Mdm2 and the HPV protein E6

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DNA Structure-Induced Recruitment and Activation of the Fanconi Anemia Pathway Protein FANCD2

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Multiple interacting domains contribute to p14ARF mediated inhibition of MDM2

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The p53 isoforms are differentially modified by Mdm2

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A Designed Peptide Targets Two Types of Modifications of p53 with Anti-cancer Activity

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An N-terminal p14ARF peptide blocks Mdm2-dependent ubiquitination in vitro and can activate p53 in vivo

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MDM2 promotes ubiquitination and degradation of MDMX

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Association of p19ARF with Mdm2 inhibits ubiquitin ligase activity of Mdm2 for tumor suppressor p53

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Bivalent binding of p14ARF to MDM2 RING and acidic domains inhibits E3 ligase function

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