Grossman, Sharon R.

Activity-by-contact model of enhancer–promoter regulation from thousands of CRISPR perturbations

Fulco, C. P., Nasser, J., Jones, T. R., Munson, G., Bergman, D. T., Subramanian, V., Grossman, S. R., Anyoha, R., Doughty, B. R., Patwardhan, T. A., et al. (2019) · Nature Genetics

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 1,111

Detecting Natural Selection in Genomic Data

Vitti, J. J., Grossman, S. R., & Sabeti, P. C. (2013) · Annual Review of Genetics

Evolution and Genetic DynamicsGenetic diversity and population structure

Cited by 694

Systematic mapping of functional enhancer–promoter connections with CRISPR interference

Fulco, C. P., Munschauer, M., Anyoha, R., Munson, G., Grossman, S. R., Perez, E. M., Kane, M., Cleary, B., Lander, E. S., & Engreitz, J. M. (2016) · Science

Genomics and Chromatin DynamicsCRISPR and Genetic Engineering

Cited by 643

A Composite of Multiple Signals Distinguishes Causal Variants in Regions of Positive Selection

Grossman, S. R., Shylakhter, I., Karlsson, E. K., Byrne, E. H., Morales, S., Frieden, G., Hostetter, E., Angelino, E., Garber, M., Zuk, O., et al. (2010) · Science

Genetic Associations and EpidemiologyForensic and Genetic Research

Cited by 512

Identifying Recent Adaptations in Large-Scale Genomic Data

Grossman, S. R., Andersen, K. G., Shlyakhter, I., Tabrizi, S., Winnicki, S., Yen, A., Park, D. J., Griesemer, D., Karlsson, E. K., Wong, S. H., et al. (2013) · Cell

Genetic Associations and EpidemiologyEvolution and Genetic Dynamics

Cited by 368

Systematic dissection of genomic features determining transcription factor binding and enhancer function

Grossman, S. R., Zhang, X., Wang, L., Engreitz, J., Melnikov, A., Rogov, P., Tewhey, R., Isakova, A., Deplancke, B., Bernstein, B. E., et al. (2017) · Proceedings of the National Academy of Sciences

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 165

Detecting genome-wide directional effects of transcription factor binding on polygenic disease risk

Reshef, Y. A., Finucane, H. K., Kelley, D. R., Gusev, A., Kotliar, D., Ulirsch, J. C., Hormozdiari, F., Nasser, J., O’Connor, L., van de Geijn, B., et al. (2018) · Nature Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 68