Mulero, Francisca

Sirt1 improves healthy ageing and protects from metabolic syndrome-associated cancer

Herranz, D., Muñoz-Martin, M., Cañamero, M., Mulero, F., Martinez-Pastor, B., Fernandez-Capetillo, O., & Serrano, M. (2010) · Nature Communications

Sirtuins and Resveratrol in MedicineGenetics, Aging, and Longevity in Model Organisms

Cited by 612

A Synthetic Lethal Interaction between K-Ras Oncogenes and Cdk4 Unveils a Therapeutic Strategy for Non-small Cell Lung Carcinoma

Puyol, M., Martín, A., Dubus, P., Mulero, F., Pizcueta, P., Khan, G., Guerra, C., Santamaría, D., & Barbacid, M. (2010) · Cancer Cell

Telomeres, Telomerase, and SenescenceCancer-related Molecular Pathways

Cited by 415

Pten positively regulates brown adipose function, energy expenditure, and longevity

Ortega-Molina, A., Efeyan, A., Lopez-Guadamillas, E., Muñoz-Martin, M., Gómez-López, G., Cañamero, M., Mulero, F., Pastor, J., Martinez, S., Romanos, E., et al. (2012) · Cell Metabolism

Adipose Tissue and MetabolismMetabolism, Diabetes, and Cancer

Cited by 356

A versatile drug delivery system targeting senescent cells

Muñoz‐Espín, D., Rovira, M., Galiana, I., Giménez, C., Lozano‐Torres, B., Paez‐Ribes, M., Llanos, S., Chaib, S., Muñoz‐Martín, M., Ucero, A. C., et al. (2018) · EMBO Molecular Medicine

Telomeres, Telomerase, and SenescenceNanoparticle-Based Drug Delivery

Cited by 339

Mice with Pulmonary Fibrosis Driven by Telomere Dysfunction

Povedano, J. M., Martinez, P., Flores, J. M., Mulero, F., & Blasco, M. A. (2015) · Cell Reports

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisTelomeres, Telomerase, and Senescence

Cited by 225

Telomerase expression confers cardioprotection in the adult mouse heart after acute myocardial infarction

Bär, C., de Jesus, B. B., Serrano, R., Tejera, A., Ayuso, E., Jimenez, V., Formentini, I., Bobadilla, M., Mizrahi, J., de Martino, A., et al. (2014) · Nature Communications

Congenital heart defects researchTelomeres, Telomerase, and Senescence

Cited by 162

Complete regression of advanced pancreatic ductal adenocarcinomas upon combined inhibition of EGFR and C-RAF

Blasco, M. T., Navas, C., Martín-Serrano, G., Graña-Castro, O., Lechuga, C. G., Martín-Díaz, L., Djurec, M., Li, J., Morales-Cacho, L., Esteban-Burgos, L., et al. (2019) · Cancer Cell

Pancreatic and Hepatic Oncology ResearchProtein Kinase Regulation and GTPase Signaling

Cited by 115

Targeting tumor mitochondrial metabolism overcomes resistance to antiangiogenics

Navarro, P., Bueno, M. J., Zagorac, I., Mondejar, T., Sanchez, J., Mourón, S., Muñoz, J., Gómez-López, G., Jimenez-Renard, V., Mulero, F., et al. (2016) · Cell Reports

Cancer, Hypoxia, and MetabolismMetabolism, Diabetes, and Cancer

Cited by 102

K-Ras V14I recapitulates Noonan syndrome in mice

Hernández-Porras, I., Fabbiano, S., Schuhmacher, A. J., Aicher, A., Cañamero, M., Cámara, J. A., Cussó, L., Desco, M., Heeschen, C., Mulero, F., et al. (2014) · Proceedings of the National Academy of Sciences

Protein Tyrosine PhosphatasesProtein Kinase Regulation and GTPase Signaling

Cited by 96

Kras oncogene ablation prevents resistance in advanced lung adenocarcinomas

Salmón, M., Álvarez-Díaz, R., Fustero-Torre, C., Brehey, O., Lechuga, C. G., Sanclemente, M., Fernández-García, F., López-García, A., Martín-Guijarro, M. C., Rodríguez-Perales, S., et al. (2023) · Journal of Clinical Investigation

Lung Cancer Treatments and MutationsProtein Kinase Regulation and GTPase Signaling

Cited by 52