Paietta, Elisabeth

Leukemic IDH1 and IDH2 Mutations Result in a Hypermethylation Phenotype, Disrupt TET2 Function, and Impair Hematopoietic Differentiation

Figueroa, M. E., Abdel-Wahab, O., Lu, C., Ward, P. S., Patel, J., Shih, A., Li, Y., Bhagwat, N., Vasanthakumar, A., Fernandez, H. F., et al. (2010) · Cancer Cell

Acute Myeloid Leukemia ResearchEpigenetics and DNA Methylation

Cited by 2,766

Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies

Abdel-Wahab, O., Mullally, A., Hedvat, C., Garcia-Manero, G., Patel, J., Wadleigh, M., Malinge, S., Yao, J., Kilpivaara, O., Bhat, R., et al. (2009) · Blood

Acute Myeloid Leukemia ResearchMyeloproliferative Neoplasms: Diagnosis and Treatment

Cited by 727

Base-Pair Resolution DNA Methylation Sequencing Reveals Profoundly Divergent Epigenetic Landscapes in Acute Myeloid Leukemia

Akalin, A., Garrett-Bakelman, F. E., Kormaksson, M., Busuttil, J., Zhang, L., Khrebtukova, I., Milne, T. A., Huang, Y., Biswas, D., Hess, J. L., et al. (2012) · PLoS Genetics

Epigenetics and DNA MethylationAcute Myeloid Leukemia Research

Cited by 296

DNMT3A mutations promote anthracycline resistance in acute myeloid leukemia via impaired nucleosome remodeling

Guryanova, O. A., Shank, K., Spitzer, B., Luciani, L., Koche, R. P., Garrett-Bakelman, F. E., Ganzel, C., Durham, B. H., Mohanty, A., Hoermann, G., et al. (2016) · Nature Medicine

Acute Myeloid Leukemia ResearchChromatin Remodeling and Cancer

Cited by 256

Chemotherapy Induces Senescence-Like Resilient Cells Capable of Initiating AML Recurrence

Duy, C., Li, M., Teater, M., Meydan, C., Garrett-Bakelman, F. E., Lee, T. C., Chin, C. R., Durmaz, C., Kawabata, K. C., Dhimolea, E., et al. (2021) · Cancer Discovery

Acute Myeloid Leukemia ResearchTelomeres, Telomerase, and Senescence

Cited by 253

Mutational Cooperativity Linked to Combinatorial Epigenetic Gain of Function in Acute Myeloid Leukemia

Shih, A. H., Jiang, Y., Meydan, C., Shank, K., Pandey, S., Barreyro, L., Antony-Debre, I., Viale, A., Socci, N., Sun, Y., et al. (2015) · Cancer Cell

Acute Myeloid Leukemia ResearchRetinoids in leukemia and cellular processes

Cited by 236

Overexpression of IL-1 receptor accessory protein in stem and progenitor cells and outcome correlation in AML and MDS

Barreyro, L., Will, B., Bartholdy, B., Zhou, L., Todorova, T. I., Stanley, R. F., Ben-Neriah, S., Montagna, C., Parekh, S., Pellagatti, A., et al. (2012) · Blood

Acute Myeloid Leukemia ResearchHematopoietic Stem Cell Transplantation

Cited by 201

New IDH1 mutant inhibitors for treatment of acute myeloid leukemia

Okoye-Okafor, U. C., Bartholdy, B., Cartier, J., Gao, E. N., Pietrak, B., Rendina, A. R., Rominger, C., Quinn, C., Smallwood, A., Wiggall, K. J., et al. (2015) · Nature Chemical Biology

Acute Myeloid Leukemia ResearchGlioma Diagnosis and Treatment

Cited by 180

Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia

Chen, Z., Shojaee, S., Buchner, M., Geng, H., Lee, J. W., Klemm, L., Titz, B., Graeber, T. G., Park, E., Tan, Y. X., et al. (2015) · Nature

Acute Lymphoblastic Leukemia researchT-cell and B-cell Immunology

Cited by 149

IL1RAP potentiates multiple oncogenic signaling pathways in AML

Mitchell, K., Barreyro, L., Todorova, T. I., Taylor, S. J., Antony-Debré, I., Narayanagari, S.-R., Carvajal, L. A., Leite, J., Piperdi, Z., Pendurti, G., et al. (2018) · Journal of Experimental Medicine

Acute Myeloid Leukemia ResearchRetinoids in leukemia and cellular processes

Cited by 97

Aberrant GSK3β nuclear localization promotes AML growth and drug resistance

Ignatz-Hoover, J. J., Wang, V., Mackowski, N. M., Roe, A. J., Ghansah, I. K., Ueda, M., Lazarus, H. M., de Lima, M., Paietta, E., Fernandez, H., et al. (2018) · Blood Advances

Acute Myeloid Leukemia ResearchChronic Myeloid Leukemia Treatments

Cited by 27

Telomere length recovery: a strong predictor of overall survival in acute promyelocytic leukemia

Baljevic, M., Dumitriu, B., Lee, J.-W., Paietta, E. M., Wiernik, P. H., Racevskis, J., Chen, C., Stein, E. M., Gallagher, R. E., Rowe, J. M., et al. (2016) · Acta Haematologica

Telomeres, Telomerase, and SenescenceRetinoids in leukemia and cellular processes

Cited by 20