Ashford, Michael L. J.

Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1

Mills, E. L., Ryan, D. G., Prag, H. A., Dikovskaya, D., Menon, D., Zaslona, Z., Jedrychowski, M. P., Costa, A. S. H., Higgins, M., Hams, E., et al. (2018) · Nature

Genomics, phytochemicals, and oxidative stressImmune cells in cancer

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Leptin inhibits hypothalamic neurons by activation of ATP-sensitive potassium channels

Spanswick, D., Smith, M. A., Groppi, V. E., Logan, S. D., & Ashford, M. L. J. (1997) · Nature

Regulation of Appetite and ObesityIon channel regulation and function

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Insulin activates ATP-sensitive K+ channels in hypothalamic neurons of lean, but not obese rats

Spanswick, D., Smith, M. A., Mirshamsi, S., Routh, V. H., & Ashford, M. L. J. (2000) · Nature Neuroscience

Regulation of Appetite and ObesityIon channel regulation and function

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AMPK: Regulating Energy Balance at the Cellular and Whole Body Levels

Hardie, D. G., & Ashford, M. L. J. (2014) · Physiology

Metabolism, Diabetes, and CancerRegulation of Appetite and Obesity

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Neuronal development is promoted by weakened intrinsic antioxidant defences due to epigenetic repression of Nrf2

Bell, K. F. S., Al-Mubarak, B., Martel, M.-A., McKay, S., Wheelan, N., Hasel, P., Márkus, N. M., Baxter, P., Deighton, R. F., Serio, A., et al. (2015) · Nature Communications

Genomics, phytochemicals, and oxidative stressRedox biology and oxidative stress

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Leptin and insulin stimulation of signalling pathways in arcuate nucleus neurones: PI3K dependent actin reorganization and KATPchannel activation

Mirshamsi, S., Laidlaw, H. A., Ning, K., Anderson, E., Burgess, L. A., Gray, A., Sutherland, C., & Ashford, M. L. (2004) · BMC Neuroscience

Regulation of Appetite and ObesityHypothalamic control of reproductive hormones

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The unfolded protein response is activated in skeletal muscle by high-fat feeding: potential role in the downregulation of protein synthesis

Deldicque, L., Cani, P. D., Philp, A., Raymackers, J.-M., Meakin, P. J., Ashford, M. L. J., Delzenne, N. M., Francaux, M., & Baar, K. (2010) · American Journal of Physiology-Endocrinology and Metabolism

Endoplasmic Reticulum Stress and DiseaseMuscle metabolism and nutrition

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The physiology and pathophysiology of the neural control of the counterregulatory response

Beall, C., Ashford, M. L., & McCrimmon, R. J. (2012) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology

Diabetes Management and ResearchPancreatic function and diabetes

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