Wick, Wolfgang

EANO guidelines on the diagnosis and treatment of diffuse gliomas of adulthood

Weller, M., van den Bent, M., Preusser, M., Le Rhun, E., Tonn, J. C., Minniti, G., Bendszus, M., Balana, C., Chinot, O., Dirven, L., et al. (2021) · Nature Reviews Clinical Oncology

Glioma Diagnosis and TreatmentAdvanced Neuroimaging Techniques and Applications

Cited by 2,048

An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor

Opitz, C. A., Litzenburger, U. M., Sahm, F., Ott, M., Tritschler, I., Trump, S., Schumacher, T., Jestaedt, L., Schrenk, D., Weller, M., et al. (2011) · Nature

Tryptophan and brain disordersToxic Organic Pollutants Impact

Cited by 1,898

Hotspot Mutations in H3F3A and IDH1 Define Distinct Epigenetic and Biological Subgroups of Glioblastoma

Sturm, D., Witt, H., Hovestadt, V., Khuong-Quang, D.-A., Jones, D. T. W., Konermann, C., Pfaff, E., Tönjes, M., Sill, M., Bender, S., et al. (2012) · Cancer Cell

Glioma Diagnosis and TreatmentChromatin Remodeling and Cancer

Cited by 1,828

Glutamatergic synaptic input to glioma cells drives brain tumour progression

Venkataramani, V., Tanev, D. I., Strahle, C., Studier-Fischer, A., Fankhauser, L., Kessler, T., Körber, C., Kardorff, M., Ratliff, M., Xie, R., et al. (2019) · Nature

Glioma Diagnosis and TreatmentNeuroscience and Neuropharmacology Research

Cited by 1,197

Glioblastoma in adults: a Society for Neuro-Oncology (SNO) and European Society of Neuro-Oncology (EANO) consensus review on current management and future directions

Wen, P. Y., Weller, M., Lee, E. Q., Alexander, B. M., Barnholtz-Sloan, J. S., Barthel, F. P., Batchelor, T. T., Bindra, R. S., Chang, S. M., Chiocca, E. A., et al. (2020) · Neuro-Oncology

Glioma Diagnosis and TreatmentOvarian cancer diagnosis and treatment

Cited by 1,168

Cilengitide combined with standard treatment for patients with newly diagnosed glioblastoma with methylated MGMT promoter (CENTRIC EORTC 26071-22072 study): a multicentre, randomised, open-label, phase 3 trial

Stupp, R., Hegi, M. E., Gorlia, T., Erridge, S. C., Perry, J., Hong, Y.-K., Aldape, K. D., Lhermitte, B., Pietsch, T., Grujicic, D., et al. (2014) · The Lancet Oncology

Glioma Diagnosis and TreatmentPARP inhibition in cancer therapy

Cited by 1,052

Actively personalized vaccination trial for newly diagnosed glioblastoma

Hilf, N., Kuttruff-Coqui, S., Frenzel, K., Bukur, V., Stevanović, S., Gouttefangeas, C., Platten, M., Tabatabai, G., Dutoit, V., van der Burg, S. H., et al. (2019) · Nature

Glioma Diagnosis and TreatmentImmunotherapy and Immune Responses

Cited by 938

Vorasidenib in IDH1- or IDH2-Mutant Low-Grade Glioma

Mellinghoff, I. K., van den Bent, M. J., Blumenthal, D. T., Touat, M., Peters, K. B., Clarke, J., Mendez, J., Yust-Katz, S., Welsh, L., Mason, W. P., et al. (2023) · New England Journal of Medicine

Glioma Diagnosis and TreatmentAcute Myeloid Leukemia Research

Cited by 814

EANO-ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up of patients with leptomeningeal metastasis from solid tumours

Le Rhun, E., Weller, M., Brandsma, D., Van den Bent, M., de Azambuja, E., Henriksson, R., Boulanger, T., Peters, S., Watts, C., Wick, W., et al. (2017) · Annals of Oncology

Brain Metastases and TreatmentManagement of metastatic bone disease

Cited by 637

Temozolomide chemotherapy versus radiotherapy in high-risk low-grade glioma (EORTC 22033-26033): a randomised, open-label, phase 3 intergroup study

Baumert, B. G., Hegi, M. E., van den Bent, M. J., von Deimling, A., Gorlia, T., Hoang-Xuan, K., Brandes, A. A., Kantor, G., Taphoorn, M. J. B., Hassel, M. B., et al. (2016) · The Lancet Oncology

Glioma Diagnosis and TreatmentAcute Myeloid Leukemia Research

Cited by 495

Federated learning enables big data for rare cancer boundary detection

Pati, S., Baid, U., Edwards, B., Sheller, M., Wang, S.-H., Reina, G. A., Foley, P., Gruzdev, A., Karkada, D., Davatzikos, C., et al. (2022) · Nature Communications

Privacy-Preserving Technologies in DataBrain Tumor Detection and Classification

Cited by 394

IDH mutant diffuse and anaplastic astrocytomas have similar age at presentation and little difference in survival: a grading problem for WHO

Reuss, D. E., Mamatjan, Y., Schrimpf, D., Capper, D., Hovestadt, V., Kratz, A., Sahm, F., Koelsche, C., Korshunov, A., Olar, A., et al. (2015) · Acta Neuropathologica

Glioma Diagnosis and TreatmentAcute Myeloid Leukemia Research

Cited by 348

ATRX loss refines the classification of anaplastic gliomas and identifies a subgroup of IDH mutant astrocytic tumors with better prognosis

Wiestler, B., Capper, D., Holland-Letz, T., Korshunov, A., von Deimling, A., Pfister, S. M., Platten, M., Weller, M., & Wick, W. (2013) · Acta Neuropathologica

Glioma Diagnosis and TreatmentAcute Myeloid Leukemia Research

Cited by 346

No New-Net

Isensee, F., Kickingereder, P., Wick, W., Bendszus, M., & Maier-Hein, K. H. (2019) · Lecture Notes in Computer Science

Medical Image Segmentation TechniquesBrain Tumor Detection and Classification

Cited by 341

A Phase II randomized study of galunisertib monotherapy or galunisertib plus lomustine compared with lomustine monotherapy in patients with recurrent glioblastoma

Brandes, A. A., Carpentier, A. F., Kesari, S., Sepulveda-Sanchez, J. M., Wheeler, H. R., Chinot, O., Cher, L., Steinbach, J. P., Capper, D., Specenier, P., et al. (2016) · Neuro-Oncology

Glioma Diagnosis and TreatmentOvarian cancer diagnosis and treatment

Cited by 273

Bevacizumab Prevents Brain Metastases Formation in Lung Adenocarcinoma

Ilhan-Mutlu, A., Osswald, M., Liao, Y., Gömmel, M., Reck, M., Miles, D., Mariani, P., Gianni, L., Lutiger, B., Nendel, V., et al. (2016) · Molecular Cancer Therapeutics

Brain Metastases and TreatmentAngiogenesis and VEGF in Cancer

Cited by 119

CODEL: Phase III study of RT, RT + TMZ, or TMZ for newly diagnosed 1p/19q codeleted oligodendroglioma. Analysis from the initial study design

Jaeckle, K. A., Ballman, K. V., van den Bent, M., Giannini, C., Galanis, E., Brown, P. D., Jenkins, R. B., Cairncross, J. G., Wick, W., Weller, M., et al. (2021) · Neuro-Oncology

Glioma Diagnosis and TreatmentPARP inhibition in cancer therapy

Cited by 119

Performance of large language models on a neurology board-style examination

Schubert, M. C., Wick, W., & Venkataramani, V. (2023) · JAMA Network Open

Artificial Intelligence in Healthcare and EducationInnovations in Medical Education

Cited by 115

Neurological sequelae of cancer immunotherapies and targeted therapies

Wick, W., Hertenstein, A., & Platten, M. (2016) · The Lancet Oncology

Cancer Immunotherapy and BiomarkersAutoimmune Neurological Disorders and Treatments

Cited by 87

Targeting Resistance against the MDM2 Inhibitor RG7388 in Glioblastoma Cells by the MEK Inhibitor Trametinib

Berberich, A., Kessler, T., Thomé, C. M., Pusch, S., Hielscher, T., Sahm, F., Oezen, I., Schmitt, L.-M., Ciprut, S., Hucke, N., et al. (2019) · Clinical Cancer Research

Glioma Diagnosis and TreatmentCancer-related Molecular Pathways

Cited by 75

The stress kinase GCN2 does not mediate suppression of antitumor T cell responses by tryptophan catabolism in experimental melanomas

Sonner, J. K., Deumelandt, K., Ott, M., Thomé, C. M., Rauschenbach, K. J., Schulz, S., Munteanu, B., Mohapatra, S., Adam, I., Hofer, A.-C., et al. (2016) · OncoImmunology

Cancer Immunotherapy and BiomarkersT-cell and B-cell Immunology

Cited by 64

Non-IDH1-R132H IDH1/2 mutations are associated with increased DNA methylation and improved survival in astrocytomas, compared to IDH1-R132H mutations

Tesileanu, C. M. S., Vallentgoed, W. R., Sanson, M., Taal, W., Clement, P. M., Wick, W., Brandes, A. A., Baurain, J. F., Chinot, O. L., Wheeler, H., et al. (2021) · Acta Neuropathologica

Glioma Diagnosis and TreatmentAcute Myeloid Leukemia Research

Cited by 62

Automated detection and quantification of brain metastases on clinical MRI data using artificial neural networks

Pflüger, I., Wald, T., Isensee, F., Schell, M., Meredig, H., Schlamp, K., Bernhardt, D., Brugnara, G., Heußel, C. P., Debus, J., et al. (2022) · Neuro-Oncology Advances

Brain Tumor Detection and ClassificationBrain Metastases and Treatment

Cited by 31

Supraagonistic, bispecific single‐chain antibody purified from the serum of cloned, transgenic cows induces T‐cell‐mediated killing of glioblastoma cells in vitro and in vivo

Grosse‐Hovest, L., Wick, W., Minoia, R., Weller, M., Rammensee, H., Brem, G., & Jung, G. (2005) · International Journal of Cancer

Monoclonal and Polyclonal Antibodies ResearchImmunotherapy and Immune Responses

Cited by 23