Moiseyev, Gennadiy

RPE65 is the isomerohydrolase in the retinoid visual cycle

Moiseyev, G., Chen, Y., Takahashi, Y., Wu, B. X., & Ma, J.-X. (2005) · Proceedings of the National Academy of Sciences

Retinal Development and DisordersRetinoids in leukemia and cellular processes

Cited by 536

RPE65 Is an Iron(II)-dependent Isomerohydrolase in the Retinoid Visual Cycle

Moiseyev, G., Takahashi, Y., Chen, Y., Gentleman, S., Redmond, T. M., Crouch, R. K., & Ma, J.-X. (2006) · Journal of Biological Chemistry

Retinal Development and DisordersRetinoids in leukemia and cellular processes

Cited by 119

Retinyl Esters Are the Substrate for Isomerohydrolase

Moiseyev, G., Crouch, R. K., Goletz, P., Oatis, Redmond, T. M., & Ma, J.-X. (2003) · Biochemistry

Retinal Development and DisordersRetinoids in leukemia and cellular processes

Cited by 116

A1120, a Nonretinoid RBP4 Antagonist, Inhibits Formation of Cytotoxic Bisretinoids in the Animal Model of Enhanced Retinal Lipofuscinogenesis

Dobri, N., Qin, Q., Kong, J., Yamamoto, K., Liu, Z., Moiseyev, G., Ma, J.-X., Allikmets, R., Sparrow, J. R., & Petrukhin, K. (2013) · Investigative Opthalmology & Visual Science

Retinal Diseases and TreatmentsRetinal Development and Disorders

Cited by 91

RPE65 Gene Delivery Restores Isomerohydrolase Activity and Prevents Early Cone Loss in Rpe65−/−Mice

Chen, Y., Moiseyev, G., Takahashi, Y., & Ma, J.-X. (2006) · Investigative Opthalmology & Visual Science

Retinal Development and DisordersRetinal Diseases and Treatments

Cited by 80

α-Phenyl-N-tert-butylnitrone (PBN) Prevents Light-induced Degeneration of the Retina by Inhibiting RPE65 Protein Isomerohydrolase Activity

Mandal, M. N. A., Moiseyev, G. P., Elliott, M. H., Kasus-Jacobi, A., Li, X., Chen, H., Zheng, L., Nikolaeva, O., Floyd, R. A., Ma, J.-X., et al. (2011) · Journal of Biological Chemistry

Retinal Development and DisordersRetinal Diseases and Treatments

Cited by 56

Identification of conserved histidines and glutamic acid as key residues for isomerohydrolase activity of RPE65, an enzyme of the visual cycle in the retinal pigment epithelium

Takahashi, Y., Moiseyev, G., Chen, Y., & Ma, J.-X. (2005) · FEBS Letters

Retinal Development and DisordersPhotoreceptor and optogenetics research

Cited by 54

Negative charge of the glutamic acid 417 residue is crucial for isomerohydrolase activity of RPE65

Nikolaeva, O., Takahashi, Y., Moiseyev, G., & Ma, J.-X. (2010) · Biochemical and Biophysical Research Communications

Retinal Development and DisordersRetinoids in leukemia and cellular processes

Cited by 14

Identification of the Key Residues Determining the Product Specificity of Isomerohydrolase

Takahashi, Y., Moiseyev, G., Nikolaeva, O., & Ma, J.-X. (2012) · Biochemistry

Retinal Development and DisordersRetinoids in leukemia and cellular processes

Cited by 13