Geens, Mieke

Higher-Density Culture in Human Embryonic Stem Cells Results in DNA Damage and Genome Instability

Jacobs, K., Zambelli, F., Mertzanidou, A., Smolders, I., Geens, M., Nguyen, H. T., Barbé, L., Sermon, K., & Spits, C. (2016) · Stem Cell Reports

Pluripotent Stem Cells ResearchTelomeres, Telomerase, and Senescence

Cited by 82

Gain of 20q11.21 in Human Pluripotent Stem Cells Impairs TGF-β-Dependent Neuroectodermal Commitment

Markouli, C., Couvreu De Deckersberg, E., Regin, M., Nguyen, H. T., Zambelli, F., Keller, A., Dziedzicka, D., De Kock, J., Tilleman, L., Van Nieuwerburgh, F., et al. (2019) · Stem Cell Reports

Pluripotent Stem Cells ResearchDevelopmental Biology and Gene Regulation

Cited by 64

Low-grade chromosomal mosaicism in human somatic and embryonic stem cell populations

Jacobs, K., Mertzanidou, A., Geens, M., Thi Nguyen, H., Staessen, C., & Spits, C. (2014) · Nature Communications

Genomic variations and chromosomal abnormalitiesCancer Genomics and Diagnostics

Cited by 41

Female human pluripotent stem cells rapidly lose X chromosome inactivation marks and progress to a skewed methylation pattern during culture

Geens, M., Seriola, A., Barbé, L., Santalo, J., Veiga, A., Dée, K., Van Haute, L., Sermon, K., & Spits, C. (2016) · Molecular Human Reproduction

Pluripotent Stem Cells ResearchEpigenetics and DNA Methylation

Cited by 26

Uncovering low-level mosaicism in human embryonic stem cells using high throughput single cell shallow sequencing

Keller, A., Tilleman, L., Dziedzicka, D., Zambelli, F., Sermon, K., Van Nieuwerburgh, F., Spits, C., & Geens, M. (2019) · Scientific Reports

Genomic variations and chromosomal abnormalitiesSingle-cell and spatial transcriptomics

Cited by 21

Gains of 12p13.31 delay WNT-mediated initiation of hPSC differentiation and promote residual pluripotency in a cell cycle dependent manner

Keller, A., Lei, Y., Krivec, N., de Deckersberg, E. C., Dziedzicka, D., Markouli, C., Sermon, K., Geens, M., & Spits, C. (2021) · bioRxiv (Cold Spring Harbor Laboratory)

Pluripotent Stem Cells ResearchDevelopmental Biology and Gene Regulation

Cited by 10