Franchi, Luigi

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

Duewell, P., Kono, H., Rayner, K. J., Sirois, C. M., Vladimer, G., Bauernfeind, F. G., Abela, G. S., Franchi, L., Nuñez, G., Schnurr, M., et al. (2010) · Nature

Inflammasome and immune disordersAtherosclerosis and Cardiovascular Diseases

Cited by 4,026

The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis

Franchi, L., Eigenbrod, T., Muñoz-Planillo, R., & Nuñez, G. (2009) · Nature Immunology

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 1,834

Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes

Masters, S. L., Dunne, A., Subramanian, S. L., Hull, R. L., Tannahill, G. M., Sharp, F. A., Becker, C., Franchi, L., Yoshihara, E., Chen, Z., et al. (2010) · Nature Immunology

Inflammasome and immune disordersPancreatic function and diabetes

Cited by 1,330

Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1β in salmonella-infected macrophages

Franchi, L., Amer, A., Body-Malapel, M., Kanneganti, T.-D., Özören, N., Jagirdar, R., Inohara, N., Vandenabeele, P., Bertin, J., Coyle, A., et al. (2006) · Nature Immunology

Immune Response and InflammationInflammasome and immune disorders

Cited by 1,131

Cutting Edge: Reactive Oxygen Species Inhibitors Block Priming, but Not Activation, of the NLRP3 Inflammasome

Bauernfeind, F., Bartok, E., Rieger, A., Franchi, L., Núñez, G., & Hornung, V. (2011) · The Journal of Immunology

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 617

Nonclassical IL-1β Secretion Stimulated by P2X7 Receptors Is Dependent on Inflammasome Activation and Correlated with Exosome Release in Murine Macrophages

Qu, Y., Franchi, L., Nunez, G., & Dubyak, G. R. (2007) · The Journal of Immunology

Inflammasome and immune disordersAdenosine and Purinergic Signaling

Cited by 563

Regulation of Legionella Phagosome Maturation and Infection through Flagellin and Host Ipaf

Amer, A., Franchi, L., Kanneganti, T.-D., Body-Malapel, M., Özören, N., Brady, G., Meshinchi, S., Jagirdar, R., Gewirtz, A., Akira, S., et al. (2006) · Journal of Biological Chemistry

Legionella and Acanthamoeba researchInflammasome and immune disorders

Cited by 453

Differential Requirement of P2X7 Receptor and Intracellular K+ for Caspase-1 Activation Induced by Intracellular and Extracellular Bacteria

Franchi, L., Kanneganti, T.-D., Dubyak, G. R., & Núñez, G. (2007) · Journal of Biological Chemistry

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 356