Smith, Graeme C. M.
AstraZeneca (United Kingdom)
6 papers on CoChatORCID 0000-0001-8320-4057
Most cited papers
- Verified
Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy
Farmer, H., McCabe, N., Lord, C. J., Tutt, A. N. J., Johnson, D. A., Richardson, T. B., Santarosa, M., Dillon, K. J., Hickson, I., Knights, C., et al. (2005) · Nature
PARP inhibition in cancer therapyDNA Repair Mechanisms
Cited by 6,683
- Verified
Identification and characterization of a novel and specific inhibitor of the ataxia-telangiectasia mutated kinase ATM
Hickson, I., Zhao, Y., Richardson, C. J., Green, S. J., Martin, N. M. B., Orr, A. I., Reaper, P. M., Jackson, S. P., Curtin, N. J., & Smith, G. C. M. (2004) · Cancer Research
DNA Repair MechanismsEffects of Radiation Exposure
Cited by 1,220
- Verified
ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks
Jazayeri, A., Falck, J., Lukas, C., Bartek, J., Smith, G. C. M., Lukas, J., & Jackson, S. P. (2006) · Nature Cell Biology
DNA Repair MechanismsCancer-related Molecular Pathways
Cited by 1,064
- Verified
A Pathway of Double-Strand Break Rejoining Dependent upon ATM, Artemis, and Proteins Locating to γ-H2AX Foci
Riballo, E., Kühne, M., Rief, N., Doherty, A., Smith, G. C. M., Recio, M.-J., Reis, C., Dahm, K., Fricke, A., Krempler, A., et al. (2004) · Molecular Cell
DNA Repair MechanismsEffects of Radiation Exposure
Cited by 837
- Verified
AZD8055 Is a Potent, Selective, and Orally Bioavailable ATP-Competitive Mammalian Target of Rapamycin Kinase Inhibitor with In vitro and In vivo Antitumor Activity
Chresta, C. M., Davies, B. R., Hickson, I., Harding, T., Cosulich, S., Critchlow, S. E., Vincent, J. P., Ellston, R., Jones, D., Sini, P., et al. (2010) · Cancer Research
PI3K/AKT/mTOR signaling in cancerAutophagy in Disease and Therapy
Cited by 812
- Verified
ΔNp63 transcriptionally regulates ATM to control p53 Serine-15 phosphorylation
Craig, A. L., Holcakova, J., Finlan, L. E., Nekulova, M., Hrstka, R., Gueven, N., DiRenzo, J., Smith, G., Hupp, T. R., & Vojtesek, B. (2010) · Molecular Cancer
Cancer-related Molecular PathwaysDNA Repair Mechanisms
Cited by 37
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