Thienpont, Bernard

Phenotype molding of stromal cells in the lung tumor microenvironment

Lambrechts, D., Wauters, E., Boeckx, B., Aibar, S., Nittner, D., Burton, O., Bassez, A., Decaluwé, H., Pircher, A., Van den Eynde, K., et al. (2018) · Nature Medicine

Single-cell and spatial transcriptomicsCancer Immunotherapy and Biomarkers

Cited by 1,648

Methods and applications for single-cell and spatial multi-omics

Vandereyken, K., Sifrim, A., Thienpont, B., & Voet, T. (2023) · Nature Reviews Genetics

Single-cell and spatial transcriptomicsBioinformatics and Genomic Networks

Cited by 1,244

The Dynamics of Genome-wide DNA Methylation Reprogramming in Mouse Primordial Germ Cells

Seisenberger, S., Andrews, S., Krueger, F., Arand, J., Walter, J., Santos, F., Popp, C., Thienpont, B., Dean, W., & Reik, W. (2012) · Molecular Cell

Epigenetics and DNA MethylationPluripotent Stem Cells Research

Cited by 973

A Single-Cell Transcriptome Atlas of the Aging Drosophila Brain

Davie, K., Janssens, J., Koldere, D., De Waegeneer, M., Pech, U., Kreft, Ł., Aibar, S., Makhzami, S., Christiaens, V., Bravo González-Blas, C., et al. (2018) · Cell

Single-cell and spatial transcriptomicsGenetics, Aging, and Longevity in Model Organisms

Cited by 840

Inhibition of the Glycolytic Activator PFKFB3 in Endothelium Induces Tumor Vessel Normalization, Impairs Metastasis, and Improves Chemotherapy

Cantelmo, A. R., Conradi, L.-C., Brajic, A., Goveia, J., Kalucka, J., Pircher, A., Chaturvedi, P., Hol, J., Thienpont, B., Teuwen, L.-A., et al. (2016) · Cancer Cell

Angiogenesis and VEGF in CancerCancer, Hypoxia, and Metabolism

Cited by 659

Tumour hypoxia causes DNA hypermethylation by reducing TET activity

Thienpont, B., Steinbacher, J., Zhao, H., D’Anna, F., Kuchnio, A., Ploumakis, A., Ghesquière, B., Van Dyck, L., Boeckx, B., Schoonjans, L., et al. (2016) · Nature

Epigenetics and DNA MethylationCancer, Hypoxia, and Metabolism

Cited by 635

Osteocytic oxygen sensing controls bone mass through epigenetic regulation of sclerostin

Stegen, S., Stockmans, I., Moermans, K., Thienpont, B., Maxwell, P. H., Carmeliet, P., & Carmeliet, G. (2018) · Nature Communications

Bone Metabolism and DiseasesBone health and osteoporosis research

Cited by 126

An Integrated Gene Expression Landscape Profiling Approach to Identify Lung Tumor Endothelial Cell Heterogeneity and Angiogenic Candidates

Goveia, J., Rohlenova, K., Taverna, F., Treps, L., Conradi, L.-C., Pircher, A., Geldhof, V., de Rooij, L. P. M. H., Kalucka, J., Sokol, L., et al. (2020) · Cancer Cell

Angiogenesis and VEGF in CancerSingle-cell and spatial transcriptomics

Cited by 125

Heterogeneity of repolarization and cell-cell variability of cardiomyocyte Remodeling within the myocardial infarction border zone contribute to arrhythmia susceptibility

Amoni, M., Vermoortele, D., Ekhteraei-Tousi, S., Doñate Puertas, R., Gilbert, G., Youness, M., Thienpont, B., Willems, R., Roderick, H. L., Claus, P., et al. (2023) · Circulation: Arrhythmia and Electrophysiology

Cardiac electrophysiology and arrhythmiasCardiac Fibrosis and Remodeling

Cited by 33

Benchmarking of computational demultiplexing methods for single-nucleus RNA sequencing data

Fu, Y., Youness, M., Virzì, A., Song, X., Tubeeckx, M. R. L., De Keulenaer, G. W., Heidbuchel, H., Segers, V. F. M., Sipido, K. R., Thienpont, B., et al. (2025) · Briefings in Bioinformatics

Single-cell and spatial transcriptomicsGenomics and Phylogenetic Studies

Cited by 2