Lu, Xiongbin

p53 mutant mice that display early ageing-associated phenotypes

Tyner, S. D., Venkatachalam, S., Choi, J., Jones, S., Ghebranious, N., Igelmann, H., Lu, X., Soron, G., Cooper, B., Brayton, C., et al. (2002) · Nature

Genetics, Aging, and Longevity in Model OrganismsCancer-related Molecular Pathways

Cited by 1,459

PPM1D dephosphorylates Chk1 and p53 and abrogates cell cycle checkpoints

Lu, X., Nannenga, B., & Donehower, L. A. (2005) · Genes & Development

DNA Repair MechanismsProtein Tyrosine Phosphatases

Cited by 389

Microfluidics Enabled Bottom-Up Engineering of 3D Vascularized Tumor for Drug Discovery

Agarwal, P., Wang, H., Sun, M., Xu, J., Zhao, S., Liu, Z., Gooch, K. J., Zhao, Y., Lu, X., & He, X. (2017) · ACS Nano

3D Printing in Biomedical ResearchHydrogels: synthesis, properties, applications

Cited by 168

Loss‐of‐Function Genetic Screening Identifies Aldolase A as an Essential Driver for Liver Cancer Cell Growth Under Hypoxia

Niu, Y., Lin, Z., Wan, A., Sun, L., Yan, S., Liang, H., Zhan, S., Chen, D., Bu, X., Liu, P., et al. (2021) · Hepatology

Cancer, Hypoxia, and MetabolismHepatocellular Carcinoma Treatment and Prognosis

Cited by 115

An organoid-based screen for epigenetic inhibitors that stimulate antigen presentation and potentiate T-cell-mediated cytotoxicity

Zhou, Z., Van der Jeught, K., Fang, Y., Yu, T., Li, Y., Ao, Z., Liu, S., Zhang, L., Yang, Y., Eyvani, H., et al. (2021) · Nature Biomedical Engineering

Cancer Immunotherapy and BiomarkersImmunotherapy and Immune Responses

Cited by 107

Phosphorylation and Degradation of MdmX Is Inhibited by Wip1 Phosphatase in the DNA Damage Response

Zhang, X., Lin, L., Guo, H., Yang, J., Jones, S. N., Jochemsen, A., & Lu, X. (2009) · Cancer Research

Cancer-related Molecular PathwaysProtein Tyrosine Phosphatases

Cited by 67

Noncoding RNAs in DNA Repair and Genome Integrity

Wan, G., Liu, Y., Han, C., Zhang, X., & Lu, X. (2014) · Antioxidants & Redox Signaling

Cancer-related molecular mechanisms researchDNA Repair Mechanisms

Cited by 50

The Wip1 phosphatase and Mdm2: cracking the “Wip” on p53 stability

Lu, X., Nguyen, T.-A., Zhang, X., & Donehower, L. A. (2008) · Cell Cycle

Cancer-related Molecular PathwaysProtein Tyrosine Phosphatases

Cited by 44

Protein Phosphatase 2A Acts as a Mitogen-activated Protein Kinase Kinase Kinase 3 (MEKK3) Phosphatase to Inhibit Lysophosphatidic Acid-induced IκB Kinase β/Nuclear Factor-κB Activation

Sun, W., Wang, H., Zhao, X., Yu, Y., Fan, Y., Wang, H., Wang, X., Lu, X., Zhang, G., Fu, S., et al. (2010) · Journal of Biological Chemistry

NF-κB Signaling PathwaysProtein Kinase Regulation and GTPase Signaling

Cited by 20