Baker, Darren J.

Therapy-Induced Senescence Drives Bone Loss

Yao, Z., Murali, B., Ren, Q., Luo, X., Faget, D. V., Cole, T., Ricci, B., Thotala, D., Monahan, J., van Deursen, J. M., et al. (2020) · Cancer Research

Telomeres, Telomerase, and SenescenceBone health and treatments

Cited by 129

Implicating endothelial cell senescence to dysfunction in the ageing and diseased brain

Graves, S. I., & Baker, D. J. (2020) · Basic & Clinical Pharmacology & Toxicology

Barrier Structure and Function StudiesTelomeres, Telomerase, and Senescence

Cited by 118

p21 induces a senescence program and skeletal muscle dysfunction

Englund, D. A., Jolliffe, A., Aversa, Z., Zhang, X., Sturmlechner, I., Sakamoto, A. E., Zeidler, J. D., Warner, G. M., McNinch, C., White, T. A., et al. (2023) · Molecular Metabolism

Telomeres, Telomerase, and SenescenceMuscle Physiology and Disorders

Cited by 90

Aging-Associated Vascular Phenotype in Mutant Mice With Low Levels of BubR1

Matsumoto, T., Baker, D. J., d’Uscio, L. V., Mozammel, G., Katusic, Z. S., & van Deursen, J. M. (2007) · Stroke

Cardiovascular Health and Disease PreventionNitric Oxide and Endothelin Effects

Cited by 77

Senescent cells suppress innate smooth muscle cell repair functions in atherosclerosis

Childs, B. G., Zhang, C., Shuja, F., Sturmlechner, I., Trewartha, S., Velasco, R. F., Baker, D. J., Li, H., & van Deursen, J. M. (2021) · Nature Aging

Atherosclerosis and Cardiovascular DiseasesTelomeres, Telomerase, and Senescence

Cited by 76

Untangling senescent and damage‐associated microglia in the aging and diseased brain

Ng, P. Y., McNeely, T. L., & Baker, D. J. (2023) · The FEBS Journal

Neuroinflammation and Neurodegeneration MechanismsGenetics, Aging, and Longevity in Model Organisms

Cited by 68

Transfer learning in a biomaterial fibrosis model identifies in vivo senescence heterogeneity and contributions to vascularization and matrix production across species and diverse pathologies

Cherry, C., Andorko, J. I., Krishnan, K., Mejías, J. C., Nguyen, H. H., Stivers, K. B., Gray-Gaillard, E. F., Ruta, A., Han, J., Hamada, N., et al. (2023) · GeroScience

Telomeres, Telomerase, and SenescenceSingle-cell and spatial transcriptomics

Cited by 66

The yin and yang of the Cdkn2a locus in senescence and aging

Baker, D. J., Jin, F., & van Deursen, J. M. (2008) · Cell Cycle

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 56

Single-cell and spatial transcriptomics map senescent vascular cells in arterial remodeling during atherosclerosis in mice

Mazan-Mamczarz, K., Tsitsipatis, D., Childs, B. G., Carr, A. E., Dos Santos, C. R., Anerillas, C., Romero, B., Gregg, J. M., Henry-Smith, C., Okereke, A. N., et al. (2025) · Nature Aging

Telomeres, Telomerase, and SenescenceAtherosclerosis and Cardiovascular Diseases

Cited by 48

Insights from In Vivo Studies of Cellular Senescence

Prieto, L. I., Graves, S. I., & Baker, D. J. (2020) · Cells

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 41

Age-related decline in BubR1 impairs adult hippocampal neurogenesis

Yang, Z., Jun, H., Choi, C.-I., Yoo, K. H., Cho, C. H., Hussaini, S. M. Q., Simmons, A. J., Kim, S., van Deursen, J. M., Baker, D. J., et al. (2017) · Aging Cell

Neurogenesis and neuroplasticity mechanismsMemory and Neural Mechanisms

Cited by 40

Advancing biological understanding of cellular senescence with computational multiomics

Li, S., Agudelo Garcia, P. A., Aliferis, C., Becich, M. J., Calyeca, J., Cosgrove, B. D., Elisseeff, J., Farzad, N., Fertig, E. J., Glass, C., et al. (2025) · Nature Genetics

Telomeres, Telomerase, and SenescenceSingle-cell and spatial transcriptomics

Cited by 40

The progeroid gene BubR1 regulates axon myelination and motor function

Choi, C.-I., Yoo, K. H., Hussaini, S. M. Q., Jeon, B. T., Welby, J., Gan, H., Scarisbrick, I. A., Zhang, Z., Baker, D. J., van Deursen, J. M., et al. (2016) · Aging

Neurogenesis and neuroplasticity mechanismsMultiple Sclerosis Research Studies

Cited by 26

Senescence in aging and disorders of the central nervous system

Swenson, B. L., Meyer, C. F., Bussian, T. J., & Baker, D. J. (2019) · Translational Medicine of Aging

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 24