Ambudkar, Suresh V.

A "Silent" Polymorphism in the MDR 1 Gene Changes Substrate Specificity

Kimchi-Sarfaty, C., Oh, J. M., Kim, I.-W., Sauna, Z. E., Calcagno, A. M., Ambudkar, S. V., & Gottesman, M. M. (2007) · Science

Drug Transport and Resistance MechanismsPharmacogenetics and Drug Metabolism

Cited by 2,416

Redefining the relevance of established cancer cell lines to the study of mechanisms of clinical anti-cancer drug resistance

Gillet, J.-P., Calcagno, A. M., Varma, S., Marino, M., Green, L. J., Vora, M. I., Patel, C., Orina, J. N., Eliseeva, T. A., Singal, V., et al. (2011) · Proceedings of the National Academy of Sciences

Drug Transport and Resistance MechanismsCancer Cells and Metastasis

Cited by 477

Lapatinib (Tykerb, GW572016) Reverses Multidrug Resistance in Cancer Cells by Inhibiting the Activity of ATP-Binding Cassette Subfamily B Member 1 and G Member 2

Dai, C.-L., Tiwari, A. K., Wu, C.-P., Su, X.-D., Wang, S.-R., Liu, D.-G., Ashby, C. R., Huang, Y., Robey, R. W., Liang, Y.-J., et al. (2008) · Cancer Research

Drug Transport and Resistance MechanismsAntibiotic Resistance in Bacteria

Cited by 386

Apatinib (YN968D1) Reverses Multidrug Resistance by Inhibiting the Efflux Function of Multiple ATP-Binding Cassette Transporters

Mi, Y.-J., Liang, Y.-J., Huang, H.-B., Zhao, H.-Y., Wu, C.-P., Wang, F., Tao, L.-Y., Zhang, C.-Z., Dai, C.-L., Tiwari, A. K., et al. (2010) · Cancer Research

Drug Transport and Resistance MechanismsAntibiotic Resistance in Bacteria

Cited by 337

The Inhibitor Ko143 Is Not Specific for ABCG2

Weidner, L. D., Zoghbi, S. S., Lu, S., Shukla, S., Ambudkar, S. V., Pike, V. W., Mulder, J., Gottesman, M. M., Innis, R. B., & Hall, M. D. (2015) · The Journal of Pharmacology and Experimental Therapeutics

Drug Transport and Resistance MechanismsBarrier Structure and Function Studies

Cited by 141

Functional Characterization of Candida albicans ABC Transporter Cdr1p

Shukla, S., Saini, P., Smriti, Jha, S., Ambudkar, S. V., & Prasad, R. (2003) · Eukaryotic Cell

Drug Transport and Resistance MechanismsAntifungal resistance and susceptibility

Cited by 135

The multidrug transporter Pdr5 on the 25th anniversary of its discovery: an important model for the study of asymmetric ABC transporters

Golin, J., & Ambudkar, S. V. (2015) · Biochemical Journal

Drug Transport and Resistance MechanismsATP Synthase and ATPases Research

Cited by 63

Inhibition of ABCG2-mediated transport by protein kinase inhibitors with a bisindolylmaleimide or indolocarbazole structure

Robey, R. W., Shukla, S., Steadman, K., Obrzut, T., Finley, E. M., Ambudkar, S. V., & Bates, S. E. (2007) · Molecular Cancer Therapeutics

Drug Transport and Resistance MechanismsPharmacogenetics and Drug Metabolism

Cited by 61

Screening Compounds with a Novel High-Throughput ABCB1-Mediated Efflux Assay Identifies Drugs with Known Therapeutic Targets at Risk for Multidrug Resistance Interference

Ansbro, M. R., Shukla, S., Ambudkar, S. V., Yuspa, S. H., & Li, L. (2013) · PLoS ONE

Drug Transport and Resistance MechanismsAntibiotic Resistance in Bacteria

Cited by 54

The yeast Pdr5p multidrug transporter: How does it recognize so many substrates?

Golin, J., Ambudkar, S. V., & May, L. (2007) · Biochemical and Biophysical Research Communications

Drug Transport and Resistance MechanismsAntibiotic Resistance in Bacteria

Cited by 53