Schirmacher, Peter

EASL Clinical Practice Guidelines: Management of hepatocellular carcinoma

Galle, P. R., Forner, A., Llovet, J. M., Mazzaferro, V., Piscaglia, F., Raoul, J.-L., Schirmacher, P., & Vilgrain, V. (2018) · Journal of Hepatology

Hepatocellular Carcinoma Treatment and PrognosisHepatitis B Virus Studies

Cited by 11,406

Senescence surveillance of pre-malignant hepatocytes limits liver cancer development

Kang, T.-W., Yevsa, T., Woller, N., Hoenicke, L., Wuestefeld, T., Dauch, D., Hohmeyer, A., Gereke, M., Rudalska, R., Potapova, A., et al. (2011) · Nature

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 1,621

NASH limits anti-tumour surveillance in immunotherapy-treated HCC

Pfister, D., Núñez, N. G., Pinyol, R., Govaere, O., Pinter, M., Szydlowska, M., Gupta, R., Qiu, M., Deczkowska, A., Weiner, A., et al. (2021) · Nature

Cancer Immunotherapy and BiomarkersHepatocellular Carcinoma Treatment and Prognosis

Cited by 1,294

Cdkn1a deletion improves stem cell function and lifespan of mice with dysfunctional telomeres without accelerating cancer formation

Choudhury, A. R., Ju, Z., Djojosubroto, M. W., Schienke, A., Lechel, A., Schaetzlein, S., Jiang, H., Stepczynska, A., Wang, C., Buer, J., et al. (2007) · Nature Genetics

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 426

Yes-Associated Protein Up-regulates Jagged-1 and Activates the NOTCH Pathway in Human Hepatocellular Carcinoma

Tschaharganeh, D. F., Chen, X., Latzko, P., Malz, M., Gaida, M. M., Felix, K., Ladu, S., Singer, S., Pinna, F., Gretz, N., et al. (2013) · Gastroenterology

Hippo pathway signaling and YAP/TAZCancer-related molecular mechanisms research

Cited by 326

Comprehensive Genomic and Transcriptomic Analysis for Guiding Therapeutic Decisions in Patients with Rare Cancers

Horak, P., Heining, C., Kreutzfeldt, S., Hutter, B., Mock, A., Hüllein, J., Fröhlich, M., Uhrig, S., Jahn, A., Rump, A., et al. (2021) · Cancer Discovery

Cancer Genomics and DiagnosticsGenomics and Rare Diseases

Cited by 290

In vivo RNAi screening identifies a mechanism of sorafenib resistance in liver cancer

Rudalska, R., Dauch, D., Longerich, T., McJunkin, K., Wuestefeld, T., Kang, T.-W., Hohmeyer, A., Pesic, M., Leibold, J., von Thun, A., et al. (2014) · Nature Medicine

Hepatocellular Carcinoma Treatment and PrognosisColorectal Cancer Treatments and Studies

Cited by 282

Induction of Chromosome Instability by Activation of Yes-Associated Protein and Forkhead Box M1 in Liver Cancer

Weiler, S. M. E., Pinna, F., Wolf, T., Lutz, T., Geldiyev, A., Sticht, C., Knaub, M., Thomann, S., Bissinger, M., Wan, S., et al. (2017) · Gastroenterology

Hippo pathway signaling and YAP/TAZMicrotubule and mitosis dynamics

Cited by 155

Deficiency of liver sinusoidal scavenger receptors stabilin-1 and -2 in mice causes glomerulofibrotic nephropathy via impaired hepatic clearance of noxious blood factors

Schledzewski, K., Géraud, C., Arnold, B., Wang, S., Gröne, H.-J., Kempf, T., Wollert, K. C., Straub, B. K., Schirmacher, P., Demory, A., et al. (2011) · Journal of Clinical Investigation

Chronic Kidney Disease and DiabetesRenal Diseases and Glomerulopathies

Cited by 154

A Direct In Vivo RNAi Screen Identifies MKK4 as a Key Regulator of Liver Regeneration

Wuestefeld, T., Pesic, M., Rudalska, R., Dauch, D., Longerich, T., Kang, T.-W., Yevsa, T., Heinzmann, F., Hoenicke, L., Hohmeyer, A., et al. (2013) · Cell

Liver physiology and pathologyTissue Engineering and Regenerative Medicine

Cited by 149

NEMO Prevents Steatohepatitis and Hepatocellular Carcinoma by Inhibiting RIPK1 Kinase Activity-Mediated Hepatocyte Apoptosis

Kondylis, V., Polykratis, A., Ehlken, H., Ochoa-Callejero, L., Straub, B. K., Krishna-Subramanian, S., Van, T.-M., Curth, H.-M., Heise, N., Weih, F., et al. (2015) · Cancer Cell

NF-κB Signaling PathwaysCell death mechanisms and regulation

Cited by 131

Combined interleukin 6 and soluble interleukin 6 receptor accelerates murine liver regeneration

Peters, M., Blinn, G., Jostock, T., Schirmacher, P., Büschenfelde, K. M. Z., Galle, P. R., & Rose–John, S. (2000) · Gastroenterology

Liver physiology and pathologyCytokine Signaling Pathways and Interactions

Cited by 129

Mismatch repair deficiency is a rare but putative therapeutically relevant finding in non-liver fluke associated cholangiocarcinoma

Goeppert, B., Roessler, S., Renner, M., Singer, S., Mehrabi, A., Vogel, M. N., Pathil, A., Czink, E., Köhler, B., Springfeld, C., et al. (2019) · British Journal of Cancer

Cholangiocarcinoma and Gallbladder Cancer StudiesGenetic factors in colorectal cancer

Cited by 108

FUT2 and FUT3 genotype determines CA19-9 cut-off values for detection of cholangiocarcinoma in patients with primary sclerosing cholangitis

Wannhoff, A., Hov, J. R., Folseraas, T., Rupp, C., Friedrich, K., Anmarkrud, J. A., Weiss, K. H., Sauer, P., Schirmacher, P., Boberg, K. M., et al. (2013) · Journal of Hepatology

Cholangiocarcinoma and Gallbladder Cancer StudiesLiver Diseases and Immunity

Cited by 94

Molecular signaling in multiple myeloma: association of RAS/RAF mutations and MEK/ERK pathway activation

Xu, J., Pfarr, N., Endris, V, Mai, E. K., Md Hanafiah, N. H., Lehners, N., Penzel, R., Weichert, W., Ho, A. D., Schirmacher, P., et al. (2017) · Oncogenesis

Multiple Myeloma Research and TreatmentsMelanoma and MAPK Pathways

Cited by 89

Cytoplasmic localization of the cell polarity factor scribble supports liver tumor formation and tumor cell invasiveness

Wan, S., Meyer, A., Weiler, S. M. E., Rupp, C., Tóth, M., Sticht, C., Singer, S., Thomann, S., Roessler, S., Schorpp‐Kistner, M., et al. (2018) · Hepatology

Hepatocellular Carcinoma Treatment and PrognosisHippo pathway signaling and YAP/TAZ

Cited by 79

Endothelial transdifferentiation in hepatocellular carcinoma: loss of Stabilin‐2 expression in peri‐tumourous liver correlates with increased survival

Géraud, C., Mogler, C., Runge, A., Evdokimov, K., Lu, S., Schledzewski, K., Arnold, B., Hämmerling, G., Koch, P. S., Breuhahn, K., et al. (2013) · Liver International

Angiogenesis and VEGF in CancerHepatocellular Carcinoma Treatment and Prognosis

Cited by 69

Genome-wide genetic and epigenetic analyses of pancreatic acinar cell carcinomas reveal aberrations in genome stability

Jäkel, C., Bergmann, F., Toth, R., Assenov, Y., van der Duin, D., Strobel, O., Hank, T., Klöppel, G., Dorrell, C., Grompe, M., et al. (2017) · Nature Communications

Pancreatic and Hepatic Oncology ResearchCancer Genomics and Diagnostics

Cited by 69

Fut2 genotype is a risk factor for dominant stenosis and biliary candida infections in primary sclerosing cholangitis

Rupp, C., Friedrich, K., Folseraas, T., Wannhoff, A., Bode, K. A., Weiss, K. ‐., Schirmacher, P., Sauer, P., Stremmel, W., & Gotthardt, D. N. (2014) · Alimentary Pharmacology & Therapeutics

Liver Diseases and ImmunityPediatric Hepatobiliary Diseases and Treatments

Cited by 38

Inflammation but not biliary obstruction is associated with carbohydrate antigen 19-9 levels in patients with primary sclerosing cholangitis

Wannhoff, A., Rupp, C., Friedrich, K., Brune, M., Knierim, J., Flechtenmacher, C., Sauer, P., Stremmel, W., Hov, J. R., Schirmacher, P., et al. (2015) · Clinical Gastroenterology and Hepatology

Liver Diseases and ImmunityGallbladder and Bile Duct Disorders

Cited by 34

Structure and content of the EU-IVDR: Current status and implications for pathology

Kahles, A., Goldschmid, H., Volckmar, A.-L., Ploeger, C., Kazdal, D., Penzel, R., Budczies, J., Kempny, G., Kazmierczak, M., Flechtenmacher, C., et al. (2023) · Die Pathologie

Healthcare RegulationClinical Laboratory Practices and Quality Control

Cited by 27

Spatiotemporal analysis of tumour-infiltrating immune cells in biliary carcinogenesis

Charbel, A., Tavernar, L., Albrecht, T., Brinkmann, F., Verheij, J., Roos, E., Vogel, M. N., Köhler, B., Springfeld, C., Brobeil, A., et al. (2022) · British Journal of Cancer

Cholangiocarcinoma and Gallbladder Cancer StudiesGallbladder and Bile Duct Disorders

Cited by 11