Thornburg, Zane R.

Fundamental behaviors emerge from simulations of a living minimal cell

Thornburg, Z. R., Bianchi, D. M., Brier, T. A., Gilbert, B. R., Earnest, E. E., Melo, M. C. R., Safronova, N., Sáenz, J. P., Cook, A. T., Wise, K. S., et al. (2022) · Cell

Lipid Membrane Structure and BehaviorLipid metabolism and biosynthesis

Cited by 165

Molecular dynamics simulation of an entire cell

Stevens, J. A., Grünewald, F., van Tilburg, P. A. M., König, M., Gilbert, B. R., Brier, T. A., Thornburg, Z. R., Luthey-Schulten, Z., & Marrink, S. J. (2023) · Frontiers in Chemistry

Protein Structure and DynamicsAdvanced Physical and Chemical Molecular Interactions

Cited by 156

Bringing the genetically minimal cell to life on a computer in 4D

Thornburg, Z. R., Maytin, A., Kwon, J., Brier, T. A., Gilbert, B. R., Fu, E., Gao, Y.-L., Quenneville, J., Wu, T., Li, H., et al. (2026) · Cell

Gene Regulatory Network AnalysisRNA and protein synthesis mechanisms

Cited by 44

Bringing the Genetically Minimal Cell to Life on a Computer in 4D

Thornburg, Z. R., Maytin, A., Kwon, J., Brier, T. A., Gilbert, B. R., Fu, E., Gao, Y.-L., Quenneville, J., Wu, T., Li, H., et al. (2025) · Cell

Gene Regulatory Network AnalysisRNA and protein synthesis mechanisms

Cited by 44

‘Generating chromosome geometries in a minimal cell from cryo-electron tomograms and chromosome conformation capture maps’

Gilbert, B. R., Thornburg, Z. R., Lam, V., Rashid, F.-Z. M., Glass, J. I., Villa, E., Dame, R. T., & Luthey-Schulten, Z. (2021) · Frontiers in Molecular Biosciences

Genomics and Chromatin DynamicsRNA and protein synthesis mechanisms

Cited by 30

Integrating cellular and molecular structures and dynamics into whole-cell models

Luthey-Schulten, Z., Thornburg, Z. R., & Gilbert, B. R. (2022) · Current Opinion in Structural Biology

Gene Regulatory Network AnalysisProtein Structure and Dynamics

Cited by 23

Kinetic modeling of the genetic information processes in a minimal cell

Thornburg, Z. R., Melo, M. C. R., Bianchi, D., Brier, T. A., Crotty, C., Breuer, M., Smith, H. O., Hutchison, C. A., Glass, J. I., & Luthey-Schulten, Z. (2019) · Frontiers in Molecular Biosciences

Microbial Metabolic Engineering and BioproductionGene Regulatory Network Analysis

Cited by 22

Dynamics of chromosome organization in a minimal bacterial cell

Gilbert, B. R., Thornburg, Z. R., Brier, T. A., Stevens, J. A., Grünewald, F., Stone, J. E., Marrink, S. J., & Luthey-Schulten, Z. (2023) · Frontiers in Cell and Developmental Biology

Genomics and Chromatin DynamicsBacterial Genetics and Biotechnology

Cited by 19