Vattulainen, Ilpo

Martini 3: A general purpose force field for coarse-grained molecular dynamics

Souza, P. C. T., Alessandri, R., Barnoud, J., Thallmair, S., Faustino, I., Grünewald, F., Patmanidis, I., Abdizadeh, H., Bruininks, B. M. H., Wassenaar, T. A., et al. (2021) · Nature Methods

Advanced Physical and Chemical Molecular InteractionsProtein Structure and Dynamics

Cited by 1,551

Antidepressant drugs act by directly binding to TRKB neurotrophin receptors

Casarotto, P. C., Girych, M., Fred, S. M., Kovaleva, V., Moliner, R., Enkavi, G., Biojone, C., Cannarozzo, C., Sahu, M. P., Kaurinkoski, K., et al. (2021) · Cell

Treatment of Major DepressionNerve injury and regeneration

Cited by 663

Psychedelics promote plasticity by directly binding to BDNF receptor TrkB

Moliner, R., Girych, M., Brunello, C. A., Kovaleva, V., Biojone, C., Enkavi, G., Antenucci, L., Kot, E. F., Goncharuk, S. A., Kaurinkoski, K., et al. (2023) · Nature Neuroscience

Psychedelics and Drug StudiesTreatment of Major Depression

Cited by 478

Reptational dynamics in dissipative particle dynamics simulations of polymer melts

Nikunen, P., Vattulainen, I., & Karttunen, M. (2007) · Physical Review E

Rheology and Fluid Dynamics StudiesMaterial Dynamics and Properties

Cited by 146

Mechanistic principles underlying regulation of the actin cytoskeleton by phosphoinositides

Senju, Y., Kalimeri, M., Koskela, E. V., Somerharju, P., Zhao, H., Vattulainen, I., & Lappalainen, P. (2017) · Proceedings of the National Academy of Sciences

Lipid Membrane Structure and BehaviorCellular Mechanics and Interactions

Cited by 118

Assessment of mutation probabilities of KRAS G12 missense mutants and their long-timescale dynamics by atomistic molecular simulations and Markov state modeling

Pantsar, T., Rissanen, S., Dauch, D., Laitinen, T., Vattulainen, I., & Poso, A. (2018) · PLOS Computational Biology

Protein Kinase Regulation and GTPase SignalingProtein Structure and Dynamics

Cited by 85

Machine learning in the analysis of biomolecular simulations

Kaptan, S., & Vattulainen, I. (2022) · Advances in Physics: X

Protein Structure and DynamicsMachine Learning in Materials Science

Cited by 31

Mutually exclusive roles of SHARPIN in integrin inactivation and NF-κB signaling

De Franceschi, N., Peuhu, E., Parsons, M., Rissanen, S., Vattulainen, I., Salmi, M., Ivaska, J., & Pouwels, J. (2015) · PLOS ONE

Cell Adhesion Molecules ResearchNF-κB Signaling Pathways

Cited by 22

Disulfide bridge-dependent dimerization triggers FGF2 membrane translocation into the extracellular space

Lolicato, F., Steringer, J. P., Saleppico, R., Beyer, D., Fernandez-Sobaberas, J., Unger, S., Klein, S., Riegerová, P., Wegehingel, S., Müller, H.-M., et al. (2024) · eLife

Fibroblast Growth Factor ResearchCellular transport and secretion

Cited by 9

Control of Golgi- V-ATPase through Sac1-dependent co-regulation of PI(4)P and cholesterol

Zhou, X., van der Stoel, M. M., Kaptan, S., Li, H., Li, S., Hölttä, M., Vihinen, H., Jokitalo, E., Thiele, C., Pietiläinen, O., et al. (2025) · Nature Communications

Cellular transport and secretionATP Synthase and ATPases Research

Cited by 6

Control of Golgi- V-ATPase through Sac1-dependent co-regulation of PI(4)P and cholesterol

Zhou, X., van der Stoel, M. M., Kaptan, S., Li, H., Li, S., Hölttä, M., Vihinen, H., Jokitalo, E., Thiele, C., Pietiläinen, O., et al. (2024) · Nature Communications

Cellular transport and secretionATP Synthase and ATPases Research

Cited by 6

Disulfide bridge-dependent dimerization triggers FGF2 membrane translocation into the extracellular space

Lolicato, F., Steringer, J., Saleppico, R., Beyer, D., Fernandez-Sobaberas, J., Unger, S., Klein, S., Riegerová, P., Wegehingel, S., Müller, H., et al. (2023) · eLife

Fibroblast Growth Factor ResearchCellular transport and secretion

Cited by 1

Inactive β1-integrin acts as a junctional scaffold for angiopoietin/TIE2/FOXO1 signaling

Sipilä, T., Ponna, S. K., Venkatesha Murthy, A., Pink, A., Enkavi, G., Bohra, S. K., Lewna, K., Ganesh, K., Liu, Q., Korhonen, M., et al. (2026) · Journal of Clinical Investigation

Cell Adhesion Molecules ResearchAngiogenesis and VEGF in Cancer

Cited by 0

Disulfide bridge-dependent dimerization triggers FGF2 membrane translocation into the extracellular space

Lolicato, F., Steringer, J., Saleppico, R., Beyer, D., Fernandez-Sobaberas, J., Unger, S., Klein, S., Riegerová, P., Wegehingel, S., Müller, H., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory)

Fibroblast Growth Factor ResearchCellular transport and secretion

Cited by 0

Disulfide bridge-dependent dimerization triggers FGF2 membrane translocation into the extracellular space

Lolicato, F., Steringer, J. P., Saleppico, R., Beyer, D., Fernandez-Sobaberas, J., Unger, S., Klein, S., Riegerová, P., Wegehingel, S., Müller, H.-M., et al. (2024) · eLife

Fibroblast Growth Factor ResearchCellular transport and secretion

Cited by 0