Wu, Hao

Brain-Region-Specific Organoids Using Mini-bioreactors for Modeling ZIKV Exposure

Qian, X., Nguyen, H. N., Song, M. M., Hadiono, C., Ogden, S. C., Hammack, C., Yao, B., Hamersky, G. R., Jacob, F., Zhong, C., et al. (2016) · Cell

Neurogenesis and neuroplasticity mechanismsPluripotent Stem Cells Research

Cited by 2,127

Reversing DNA Methylation: Mechanisms, Genomics, and Biological Functions

Wu, H., & Zhang, Y. (2014) · Cell

Epigenetics and DNA MethylationGenetic Syndromes and Imprinting

Cited by 1,065

Genome-wide Analysis Reveals TET- and TDG-Dependent 5-Methylcytosine Oxidation Dynamics

Shen, L., Wu, H., Diep, D., Yamaguchi, S., D’Alessio, A. C., Fung, H.-L., Zhang, K., & Zhang, Y. (2013) · Cell

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 497

Epigenomic reprogramming during pancreatic cancer progression links anabolic glucose metabolism to distant metastasis

McDonald, O. G., Li, X., Saunders, T., Tryggvadottir, R., Mentch, S. J., Warmoes, M. O., Word, A. E., Carrer, A., Salz, T. H., Natsume, S., et al. (2017) · Nature Genetics

Epigenetics and DNA MethylationPancreatic and Hepatic Oncology Research

Cited by 494

Sliced Human Cortical Organoids for Modeling Distinct Cortical Layer Formation

Qian, X., Su, Y., Adam, C. D., Deutschmann, A. U., Pather, S. R., Goldberg, E. M., Su, K., Li, S., Lu, L., Jacob, F., et al. (2020) · Cell Stem Cell

Neurogenesis and neuroplasticity mechanismsPluripotent Stem Cells Research

Cited by 479

CRISPR-Edited Stem Cells in a Patient with HIV and Acute Lymphocytic Leukemia

Xu, L., Wang, J., Liu, Y., Xie, L., Su, B., Mou, D., Wang, L., Liu, T., Wang, X., Zhang, B., et al. (2019) · New England Journal of Medicine

CRISPR and Genetic EngineeringCAR-T cell therapy research

Cited by 454

U1 small nuclear ribonucleoprotein complex and RNA splicing alterations in Alzheimer’s disease

Bai, B., Hales, C. M., Chen, P.-C., Gozal, Y., Dammer, E. B., Fritz, J. J., Wang, X., Xia, Q., Duong, D. M., Street, C., et al. (2013) · Proceedings of the National Academy of Sciences

Alzheimer's disease research and treatmentsRNA Research and Splicing

Cited by 335

Prospective study of acute HIV-1 infection in adults in East Africa and Thailand.

Robb, M. L., Eller, L. A., Kibuuka, H., Rono, K., Maganga, L., Nitayaphan, S., Kroon, E., Sawe, F. K., Sinei, S., Sriplienchan, S., et al. (2016) · New England Journal of Medicine

HIV Research and TreatmentHIV/AIDS Research and Interventions

Cited by 283

Inhibition of ileal bile acid uptake protects against nonalcoholic fatty liver disease in high-fat diet–fed mice

Rao, A., Kosters, A., Mells, J. E., Zhang, W., Setchell, K. D. R., Amanso, A. M., Wynn, G. M., Xu, T., Keller, B. T., Yin, H., et al. (2016) · Science Translational Medicine

Liver Disease Diagnosis and TreatmentDrug Transport and Resistance Mechanisms

Cited by 211

Engineering a precise adenine base editor with minimal bystander editing

Chen, L., Zhang, S., Xue, N., Hong, M., Zhang, X., Zhang, D., Yang, J., Bai, S., Huang, Y., Meng, H., et al. (2023) · Nature Chemical Biology

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 202

Re-engineering the adenine deaminase TadA-8e for efficient and specific CRISPR-based cytosine base editing

Chen, L., Zhu, B., Ru, G., Meng, H., Yan, Y., Hong, M., Zhang, D., Luan, C., Zhang, S., Wu, H., et al. (2023) · Nature Biotechnology

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 156

Detect-seq reveals out-of-protospacer editing and target-strand editing by cytosine base editors

Lei, Z., Meng, H., Lv, Z., Liu, M., Zhao, H., Wu, H., Zhang, X., Liu, L., Zhuang, Y., Yin, K., et al. (2021) · Nature Methods

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 67

Integrating Next-Generation Genomic Sequencing and Mass Spectrometry To Estimate Allele-Specific Protein Abundance in Human Brain

Wingo, T. S., Duong, D. M., Zhou, M., Dammer, E. B., Wu, H., Cutler, D. J., Lah, J. J., Levey, A. I., & Seyfried, N. T. (2017) · Journal of Proteome Research

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 51

B and T Lymphocyte Attenuator Down-regulation by HIV-1 Depends on Type I Interferon and Contributes to T-Cell Hyperactivation

Zhang, Z., Xu, X., Lu, J., Zhang, S., Gu, L., Fu, J., Jin, L., Li, H., Zhao, M., Zhang, J., et al. (2011) · The Journal of Infectious Diseases

HIV Research and TreatmentT-cell and B-cell Immunology

Cited by 35